Start of introduction:
The incredible story of the PACE trial for ME/CFS | Introduction
K. JOHNSTONE
DEC 14, 2023
Several months ago I took on a huge project: to write a history of the PACE trial, a notorious 2011 clinical trial which tested treatments for myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). The PACE trial was initially hailed as a great success, but later became a notorious story about a piece of very bad science which somehow made it through the peer-review process to be published in an eminent journal, and ended up guiding the treatment of patients for a decade, causing incalculable harm. It was exposed, not by scientists or doctors, but by chronically ill citizen-scientists and a journalist.
Much has already been written about the PACE trial, but I wanted to create a brief and comprehensive overview of this story which doesn’t assume the reader has any prior knowledge.
Continues at:
https://mecfs.substack.com/p/the-incredible-story-of-the-pace-577
https://x.com/TomKindlon/status/1739484157959434243?s=20
The incredible story of the PACE trial for ME/CFS | Introduction
K. JOHNSTONE
DEC 14, 2023
Several months ago I took on a huge project: to write a history of the PACE trial, a notorious 2011 clinical trial which tested treatments for myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). The PACE trial was initially hailed as a great success, but later became a notorious story about a piece of very bad science which somehow made it through the peer-review process to be published in an eminent journal, and ended up guiding the treatment of patients for a decade, causing incalculable harm. It was exposed, not by scientists or doctors, but by chronically ill citizen-scientists and a journalist.
Much has already been written about the PACE trial, but I wanted to create a brief and comprehensive overview of this story which doesn’t assume the reader has any prior knowledge.
Continues at:
https://mecfs.substack.com/p/the-incredible-story-of-the-pace-577
https://x.com/TomKindlon/status/1739484157959434243?s=20
