Like Alex said, this research we're discussing is a part of it, not all of it, although it may well explain all of it in the long wrong (why multiple systems in the body fail, because it all ties back to deranged energy metabolism which without energy, organs don't work correctly, and presumably, pathogens prosper, immunity activates, inflammation flourishes and the end game is autoimmune diseases and micro-vascular injury, over time), at least in some subsets.
The other parts we have to work out are pathogens, which all fits in with the evidence of oxidative stress, neuroendocrine dysfunction, exercise VO2 max drop off, vascular issues, and finally cutting edge neuroimaging showing apparent changes in brain physiology etc.
The Mitochondrial part is (hopefully) unique to ME CFS, but then we have the inflammatory cascade and autoimmune diseases to decipher, diagnose and treat as well.
The diseases and syndromes in ME CFS will be multiple, complex and hard to treat, and this end game (our personal tragedy and that of our family and loved ones who go through hell with us) is the consequence of the people paid to look after you (Governments), handing the keys to your fragile health to religious propaganda merchants (BPS CFS theorists) who, of course, never went down the biological disease pathway ,as they don't understand complex multi systemic biological diseases or care for them, hence they qualified as MD's, and went into Psychiatry as its interesting and pays well.
If only we had been gifted that choice also. It would be nice to have choices one-day, not forced survival decisions.