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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Melatonin is a methyl donor (and Niacin is the opposite of that).I've been taking melatonin before sleep somedays, but it causes me to wake up at the middle of the night and have a problem falling back to sleep. @Mary, have you experienced something like this from niacin ?
I've been taking melatonin before sleep somedays, but it causes me to wake up at the middle of the night and have a problem falling back to sleep. @Mary, have you experienced something like this from niacin ?
maybe you're an over-methylator, that would explain why niacin helps