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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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About as good an excuse for being happy as anything. It might just bring out the comic in us.Forgive my frivolity. I am actually enjoying the paper, and taking it seriously. It's very interesting.
It means that those who don't have it are more likely to die in the long run, which means that though it is harmful the benefits outweigh the harm on an evolutionary scale.So, the term "evolutionary conserved " means that it is a metabolic response eons old???
It means that those who don't have it are more likely to die in the long run, which means that though it is harmful the benefits outweigh the harm on an evolutionary scale.
Is he being hidden behind? How generous of his senior colleagues to give him his big break and allow him to be the spokesperson this time .Something odd seems to have happened as he is also quoted in the Times.
He's a psychiatrist and not even well-known in CFS circles so it would be a big coincidence if he was contacted independently by 2 journalists to comment on this story.
Critics have argued the condition, also called ME, is all in the mind
Other scientists welcomed the research, but cautioned that it was too early to say what was going on. Andrew McIntosh, from the University of Edinburgh, said: “It is difficult to know whether the changes reported are a cause or an effect of CFS.”
Academics involved in the trial said they had received abuse just for doing their jobs.
Because although it's followed by a mention of Alem Matthees forcing them to release the data, it should have added that the academics' reports of receiving abuse were described as utter bollocks by the judge (I paraphrase).
Could this just be a defense mechanism of the body dealing with a pathogen for a long period of time?An analogy that comes to mind is a computer going into safe mode. Working very slow and can execute only a limited number of actions none of which at the same time.
Well if this pans out with some sort of hypo metabolism. It is pretty hard to exercise your way out of that!
''These results implicate abnormal immune activity in the pathology of exercise intolerance in CFS and are consistent with a channelopathy involving oxidative stress and nitric oxide-related toxicity''.
Source:
In Vivo. 2005 Mar-Apr;19(2):387-90.
Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS).
Snell CR1, Vanness JM, Strayer DR, Stevens SR.
''Multivariate analysis showed
no significant differences between control participants and participants with CFS for test 1. However, for test 2, participants with CFS achieved significantly lower values for oxygen consumption and workload at peak exercise and at the ventilatory or anaerobic threshold. Follow-up classification analysis differentiated between groups with an overall accuracy of 95.1%.
Source:
Phys Ther. 2013 Nov;93(11):1484-92. doi: 10.2522/ptj.20110368. Epub 2013 Jun 27.
Discriminative validity of metabolic and workload measurements for identifying people with chronic fatigue syndrome.
Snell CR1, Stevens SR, Davenport TE, Van Ness JM.
Let me guess, people who are new to ME symptoms tend to be hypermetabolic, while those with chronic symptoms show up as hypo.