Yeah what do u take from that leokitten? I've read some of itIbudilast in healthy volunteers: safety, tolerability and pharmacokinetics with single and multiple doses
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675769/
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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Yeah what do u take from that leokitten? I've read some of itIbudilast in healthy volunteers: safety, tolerability and pharmacokinetics with single and multiple doses
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675769/
Hence the term "myalgic encephalomyelitis" is clinically inaccurate and inadequate
“Our results provide evidence of neuroinflammation in CFS/ME patients, as well as evidence of the possible contribution of neuroinflammation to the pathophysiology of CFS/ME.“
''“There is, and you’ve heard it repeatedly in the last three days, a theory that CFS might reflect an ongoing activation of immune cells in the brain, not in the periphery, but in the brain”.
“Yes. If it were confirmed by multiple other investigators it would, for me, say that there is a low-grade, chronic encephalitis in these patients, that the image we clinicians have of encephalitis as an acute and often dramatic clinical presentation that can even be fatal has – may have – blinded us to the possibility that there may be an entity of long-lasting – many years long – cyclic, chronic, neuro-inflammation and that that underlies the symptoms of this illness”, commenting that it was “entirely plausible and these data are consistent with it”.
Yeah what do u take from that leokitten? I've read some of it
A good point, I've been thinking about this possibility for a long time, but here in the U.S. you know we don't have much of a choice.
They will never give me disability because I can work full-time still even though it's at a huge cost, they don't care about what is doing to my health or life outside of work. I basically have to get to the point where you and many others did where you work yourselves to the ground and the CFS gets so bad that you then require disability.
What sucks is that they won't give me "preemptive" disability for a period of like one year to improve. That's what's so terrible about ME/CFS, it breaks all the rules and what we need to get out of this disease just goes against anything insursance or disability would allow.
@Mary PTSD also seemed to be the basis for my disability. It was when my nervous system was drastically overwrought, and I was, in fact, trigerred by everything. I had to appeal the initial MD evaluation, was then seen by a psychologist.