Basilico
Florida
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- 948
Lactobacillus Fermentum is a probiotic that just appeared on my radar. I haven't tried it yet, myself, and I couldn't find any threads on it here, so I'm wondering if anyone knows about it or has any experience with it.
The main reason it's piqued my curiosity is that it appears to create and recycle glutathione. Since it is widely hypothesized that CFS/ME folks are deficient in glutathione, perhaps having a deficit of LF could explain why levels are too low. We know that CFS/ME and GI problems often go hand in hand. My husband has a noticeable improvement when he takes liposomal glutathione...perhaps supporting the gut flora that can create it endogenously is even better than supplementing it.
Despite the "Lactobacillus" name, this particular probiotic is not found in yogurt, but I have found it available in capsules on Amazon. LF was isolated from the GI system of Estonian kids (much like the E. Coli Nissile 1017 - Mutaflor - was isolated from the GI system of a German soldier who was the only one in his troop to not get sick from a water-born pathogen).
From some research I've found:
It has been established that L. fermentum strain ME-3 has double functional properties: antimicrobial activity against intestinal pathogens and high total antioxidative activity (TAA) and total antioxidative status (TAS) of intact cells and lysates, and it is characterized by a complete glutathione system: synthesis, uptake and redox turnover. The functional efficacy of the antimicrobial and antioxidative probiotic has been proven by the eradication of salmonellas and the reduction of liver and spleen granulomas in Salmonella Typhimurium-infected mice treated with the combination of ofloxacin and L. fermentum strain ME-3.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670518/
It also seems to have a beneficial effect on the cardiovascular system:
Eight weeks of consuming kefir with the antioxidative probiotic L. fermentum ME-3, reduced serum LDL-C, ox-LDL and TG values in clinically healthy volunteers with borderline-high lipid profile indices. Thus, L. fermentum ME-3 has potential to lower the risk of CVD that is tightly associated with maintenance of plasma lipid profile.
https://bmcnutr.biomedcentral.com/articles/10.1186/s40795-015-0020-z
The main reason it's piqued my curiosity is that it appears to create and recycle glutathione. Since it is widely hypothesized that CFS/ME folks are deficient in glutathione, perhaps having a deficit of LF could explain why levels are too low. We know that CFS/ME and GI problems often go hand in hand. My husband has a noticeable improvement when he takes liposomal glutathione...perhaps supporting the gut flora that can create it endogenously is even better than supplementing it.
Despite the "Lactobacillus" name, this particular probiotic is not found in yogurt, but I have found it available in capsules on Amazon. LF was isolated from the GI system of Estonian kids (much like the E. Coli Nissile 1017 - Mutaflor - was isolated from the GI system of a German soldier who was the only one in his troop to not get sick from a water-born pathogen).
From some research I've found:
It has been established that L. fermentum strain ME-3 has double functional properties: antimicrobial activity against intestinal pathogens and high total antioxidative activity (TAA) and total antioxidative status (TAS) of intact cells and lysates, and it is characterized by a complete glutathione system: synthesis, uptake and redox turnover. The functional efficacy of the antimicrobial and antioxidative probiotic has been proven by the eradication of salmonellas and the reduction of liver and spleen granulomas in Salmonella Typhimurium-infected mice treated with the combination of ofloxacin and L. fermentum strain ME-3.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670518/
It also seems to have a beneficial effect on the cardiovascular system:
Eight weeks of consuming kefir with the antioxidative probiotic L. fermentum ME-3, reduced serum LDL-C, ox-LDL and TG values in clinically healthy volunteers with borderline-high lipid profile indices. Thus, L. fermentum ME-3 has potential to lower the risk of CVD that is tightly associated with maintenance of plasma lipid profile.
https://bmcnutr.biomedcentral.com/articles/10.1186/s40795-015-0020-z
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