@nandixon
Mifepristone is a cortisol antagonist, and the protocol seems to use it for this property.
(Mimicking a drop of cortisol stimulates ACTH production)
But this may be achieve the same way by taking a high dose of cortisol followed by a stop, which would first suppress the HPA axis, but then the sudden drop would be expected to reset the axis.
I don't know if it worked with my HPT axis, but I took a small dose of T3 which suppressed my TSH for months. Then I took supplement to favour thyroid hormons production and stopped T3 after some months.
And now my fT3 level is fine, and so is my TSH, whereas they were both in the low normal ranges before i did that.
I don't know if I reset my HPT axis, or if it's just an effect of my Selenium/iodine/B6 supplementation!