AndyPR
Senior Member
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Could ME/CFS be the post-SIRS “immune paralysis” state of Compensatory Anti-Inflammatory Response Syndrome (CARS)? Or Mixed Antagonists Response Syndrome (MARS)?
The evidence we have about ME/CFS and the striking similarities between the illnesses provide a compelling argument that ME/CFS is a form of Systemic Inflammatory Response Syndrome (SIRS) as evidenced by a recent gene expression study which has so far revealed the disease as the closest resemblance to ME/CFS.
Further analysis of mRNA gene expression, in a study led by Dr. Lipkin and Dr. Mady Hornig, showed that the disease with the closest resemblance to ME/CFS is SIRS.
If this theory can be proven it would have enormous implications for funding ME/CFS research by casting a wider net to seek treatment for critically ill patients, not only for ME/CFS but for complications arising from concussion, burns, surgery, organ replacements and serious infections such as Pneumonia. The very syndromes only discussed in Surgical ICU’s that have challenged physicians for over 40 years could be the very same syndrome that has challenged ME/CFS practitioners all this time.
http://www.meaction.net/2017/02/20/is-sirs-cars-mars-and-now-pics-causing-the-chaos-in-mecfs/