Cumin! That's cuminum cyminum, the common spice found in curry, and the active molecule is most likely cuminaldehyde. It blocked my PEM 100%, and eventually resulted in a permanent cure of PEM. Sadly, no one else has reported major benefits from it, crushing my hopes for major awards and global recognition.
I think there's a lot of potential treatments for ME in botanicals, but they'll mostly be effective for a few individuals, and not effective for anyone else. If cumin worked great for me, and some mushroom worked great for someone else, the chances of them working for you or any other specific individual may be about the same as any bottle of spice picked at random off the grocery shelf. The only way to know if something will work for you is to try it yourself. Some of us end up with a pile of potential treatments that didn't work, but some of us do get lucky and find something that works. It's like a lottery: if you buy a ticket, you have only a tiny chance of winning, but it you never buy a ticket, you're guaranteed to never win.
BTW, with ME it's common to find something that works well ... for maybe a few days, but then it stops working and never works again.