Help! I can't take folate without terrible over-methylation symptoms and need it for pre-pregnancy

[dannybex]

@PeterPositive that is really bizarre -- zero vitamin D? Were you housebound or totally avoiding any sunlight?

And back to folic acid, wasn't there a thread where someone suggested that too much of even methylfolate or folinic could be oxidized to turn into 'folic acid'? Was that question ever resolved?

Thanks in advance.

 

[PeterPositive]

@PeterPositive that is really bizarre -- zero vitamin D? Were you housebound or totally avoiding any sunlight?

Yeah both

And back to folic acid, wasn't there a thread where someone suggested that too much of even methylfolate or folinic could be oxidized to turn into 'folic acid'? Was that question ever resolved?

I don't believe it was.

cheers

 

[bertiedog]

The serum blood folic acid and B12 tests have just seemed to be non-specific to me, but one possibility for elevated levels could be SIBO. Gut bacteria can produce many B vitamins, especially folate.

Elevated folic acid is what lead me to finally realize SIBO was making me very ill: migraines, inflammation, insomnia, anxiety, etc.

Thanks for this info, I have exactly the same problems and am awaiting my GI Effects test result hopefully this week. When I add in just 150 mcg folinic acid and 1000 mcg adnB12 and 1000 mcgHydroxB12 almost immediately I couldn't sleep and after 3 days ended up with horrible overmethylation symptoms which thankfully settled down when I stopped everything.

I know I have got problems with my gut, I can feel things partying every time I eat despite taking dig enzymes and HCL. I just don't know if its just yeasts which I regularly have a problem with and/or bad bacteria but I do think its highly likely I have SIBO having had compylabactor poisoning in the late 90s.

Pam

 

[Crux]

Hi @bertiedog ,

I've read that there can be both yeast, ( Candida Albicans), and bacterial overgrowth, but it's the bacteria that produce the B vitamins. ( I've edited this to not confuse the types of yeasts.)

Some bacteria utilize ( steal ) nutrients too, so, with an overgrowth, we can get deficiencies too. B12 produced in the intestines is supposedly unusable by the host, but, I wonder, because some people have had side effects from taking it, and it can be absorbed by passive diffusion.

There was a time when I would get a migraine soon after having folate fortified foods, then fermentable fiber foods, fermented foods, and so on.

I had very elevated folic acid in the blood serum, ( that's how the lab measured and termed it ), and I had been avoiding folates of all types for some months. I hadn't been tested for SIBO, but the doctor even suspected.