This is not something I've seen discussed here (could be wrong), but one of my earliest symptoms, before full blown ME/CFS was that I noticed my hair had lost its color. I was always strawberry blonde, now, mostly just blonde. Obviously not something I felt I urgently needed to discuss with doctors but I was just curious if anyone else had noticed something similar.
My skin also changed, but that would be another symptom thread.
My skin also changed, but that would be another symptom thread.