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# rsid chromosome position genotype
rs4477212 1 72017 AA
So do I just search the raw data for each rsid and then cross reference the genotype with the spreadsheet for that rsid?
In the spreadsheet the genotypes are listed with +- (+A/-G) and this is not the case in the raw data. Do I just ignore the +-'s?
Is AG equivalent to GA?
This is a pain in the ass. Wish I had just got the nutrigenomics done... sigh.
Also, if you have 2 copies of a gene, will it be listed in the raw data twice?
Your MTRR A66G +/+ (GG) is wrong, should be -/- ?
Line 3 is telling you how to translate your results into Yasko's notation, but isn't saying anything about what's normal. So for COMT 4680, line 3 says +A/-G. This means that you should put down a + for each A or T you have at that SNP, and put down a - for each G or C.
So if your SNP is AA, then you mark it down as +/+. If you are AG, then you are +/-. If you are GG, then you are -/-. And, as you mentioned earlier, A=T and G=C.
That's how I have done mine anyway, so hopefully someone will confirm this for us!
nanonug, what other interesting genes are there to look at in the 23andme profile in relation to CFS/MCS? Are there any non methylation detoxification genes? I'm sure I could go through every line in the data, but that would be painful!
If I have done this correctly, I suspect my results a very unfortunate to say the least. Does this look correct?
If I have done this correctly, I suspect my results a very unfortunate to say the least.
ACE DEL16 No Data
CBS A360A -/- (GG)
CBS C699T +/- (AG)
COMT H62H +/+ (TT)
COMT V158M +/+ (AA)
COMT L136L No Data
COMT P199P -/- (GG)
MAO-A R297R + (T)
MTHFR C677T +/+ (TT)
MTHFR A1298C +/+ (TT)
MTHFR P39P -/- (GG)
MTR A2756G +/- (AG)
MTRR H595Y -/- (CC)
MTRR K350A +/+ (AA)
MTRR R415T -/- (CC)
MTRR S257T No Data
MTRR A66G -/- (GG)
MTRR-11 A664A +/- (AG)
NOS-3 G894T No Data
SUOX S370S No Data
SUOX A628G No Data
VDR TAQ -/- (CC)
VDR FOK No Data
ACAT1-02 -/- (GG)
AHCY-01 -/- (CC)
AHCY-02 +/- (AG)
AHCY-19 -/+ (CT)
BHMT-01 No Data
BHMT-02 -/- (CC)
BHMT-04 +/+ (AA)
BHMT-08 -/- (CC)
SHMT C1420T -/- (GG)
Does this look correct?
As I understand it, A and T are synonymous, as are C and G. Correct?
These are my results if I have got them correct too. Would someone be kind enough to check mine? My results look quite different to the Genetable that was linked above, so i wonder if i got something wrong...