Just a shout out, did you ever get anywhere on excess acetylcholine?
It turns out it was not acetylcholine. I experimented with some Alpha GCP and Citicoline, and it had a totally different effect. At first it made me feel better, helped with depression and focus, but then quickly became too much and caused restless legs and brain fog, but a different feeling from what I was originally describing. Supplementing choline actually did not cause anhedonia or depression which was surprising.
I think my problem was excess neurotransmitters (serotonin, dopamine, norepinpehrine), but not acetylcholine. I believe benadryl reduces all neurotransmitters in general. I have the MAO warrior gene so I assume anything that boosts these too much will end up causing anhedonia. Of course I could be totally wrong, and it could be something else unkown.
B2 helps, R5P is more powerful. It increases MAO and breaks down neurotransmitters. I'm still trying to figure out a good balance.