Hip
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i thought immunovir also helps increase t cell function as well??
CD4 T cells perhaps.
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i thought immunovir also helps increase t cell function as well??
Do you have low CD8 T cell numbers, or low CD8 T cell activation?
I believe Echinacea, Astragalus and licorice increase CD8 T cell activation (but not cell numbers). Ref: here.
The supplement fucoidan (from brown seaweed) increases CD8 T cell numbers. Ref: here.
Note that confusingly, CD8 T cells have many different names (synonyms):
CD8 T cells
cytotoxic T lymphocytes
cytotoxic T cells
cytolytic T cells
killer T cells
T killer cell
All these names mean the same thing.
I was told it doesn't treat CD8 dysfunction.i thought immunovir also helps increase t cell function as well??
I was told it doesn't treat CD8 dysfunction.
The hope is that CD8 numbers will improve as we clear all the infections (and keep them under control). As I understand it, low CD8 numbers can occur with immune exhaustion, so that's what we're hoping is going on.
Carrie-Louise. I suggest you to read the info given by Dr Cheney on the following link as it explains more about what seems to be happening in ME and how the immune system works. http://www.anapsid.org/cnd/diagnosis/cheneyis.html
There are a lot of Th2 ➤ Th1 shifting supplements in addition to pine cone extract, including those listed here and here.anyone tried Pine cone extract?
Carrie-Louise. I suggest you to read the info given by Dr Cheney on the following link as it explains more about what seems to be happening in ME and how the immune system works. http://www.anapsid.org/cnd/diagnosis/cheneyis.html
I have long wondered if some of the success of general anti-pathogenic treatments including antibiotics and antivirals might exert some of their effect in some patients by lowering pathogen load, giving the immune system more time to rest. It might not be really treating a specific pathogen, just lowering total burden.
Is there any data to suggest ME sufferers are predisposed to get cancer?
Lastly and most importantly - if a degree of immune collapse was really part of the causative agency, I can't imagine the compensation process he theorises would work indefinitely, so wouldn't we expect to see extreme cases of almost total immune-collapse leading to AIDS-like syndromes? But so far as I know we don't see this do we?
From personal experience, I have always perceived this as an AIDS-like syndrome. But it always baffled me why doctors look right past me when I am at my worst. And I end up having to treat myself with antibiotics to get back to baseline.Thanks I read it. I have a few basic questions:
Is there any independent data on what percentage of tested patients manifest this T-shift he theorises?
Is there any data on how effective his treatment protocol is?
Is there any data to suggest ME sufferers are predisposed to get cancer?
How does this theorised T-shift and consequent susceptibility to infection square with those like myself who report, au contraire, a very high resistance to viral and bacterial infection?
Lastly and most importantly - if a degree of immune collapse was really part of the causative agency, I can't imagine the compensation process he theorises would work indefinitely, so wouldn't we expect to see extreme cases of almost total immune-collapse leading to AIDS-like syndromes? But so far as I know we don't see this do we?
There are a lot of Th2 ➤ Th1 shifting supplements in addition to pine cone extract, including those listed here and here.
I have experimented with simultaneously taking around a dozen of the most potent Th2 ➤ Th1 shifters listed in those above weblinks, in order to create a massive shift to Th1 in my body. ...etc
Let's not forget that it's not just a Th2/Th1 thing. Someone fairly recently (~5 years) discovered a Th-17 pathway (?) which may be a big player in ME/CFS. "Low Th-17 levels may leave the host susceptible to to opportunistic infectsions" according to my immune report.
Let's not forget that it's not just a Th2/Th1 thing. Someone fairly recently (~5 years) discovered a Th-17 pathway (?) which may be a big player in ME/CFS. "Low Th-17 levels may leave the host susceptible to to opportunistic infections" according to my immune report.
Is there any independent data on what percentage of tested patients manifest this T-shift he theorises?
Is there any data on how effective his treatment protocol is?
Is there any data to suggest ME sufferers are predisposed to get cancer?
How does this theorised T-shift and consequent susceptibility to infection square with those like myself who report, au contraire, a very high resistance to viral and bacterial infection?
Lastly and most importantly - if a degree of immune collapse was really part of the causative agency, I can't imagine the compensation process he theorises would work indefinitely, so wouldn't we expect to see extreme cases of almost total immune-collapse leading to AIDS-like syndromes? But so far as I know we don't see this do we?
CFS was associated with an increased risk of non-Hodgkin lymphoma (NHL) (OR = 1.29, 95% confidence interval [CI] = 1.16-1.43, P = 1.7 × 10(-6) ). Among NHL subtypes, CFS was associated with diffuse large B cell lymphoma (OR = 1.34, 95% CI = 1.12-1.61), marginal zone lymphoma (OR = 1.88, 95% CI = 1.38-2.57), and B cell NHL not otherwise specified (OR = 1.51, 95% CI = 1.03-2.23). CFS associations with NHL overall and NHL subtypes remained elevated after excluding patients with medical conditions related to CFS or NHL, such as autoimmune conditions. CFS was also associated, although not after multiple comparison adjustment, with cancers of the pancreas (OR = 1.25, 95% CI = 1.07-1.47), kidney (OR = 1.27, 95% CI = 1.07-1.49), breast (OR = 0.85, 95% CI = 0.74-0.98), and oral cavity and pharynx (OR = 0.70, 95% CI = 0.49-1.00).
CONCLUSIONS:
Chronic immune activation or an infection associated with CFS may play a role in explaining the increased risk of NHL.
Th-17 ? Good grief. More stuff to google
I have been looking into the Th17 immune response and its role in ME/CFS. Like Th1, the Th17 immune response has also been found to be low in ME/CFS, at least in this study; but from what I can tell, it seems that Th17 might be undesirable in ME/CFS anyway, for the following reasons:
along with the following diagram.ROR gamma t deficiency results in diminished Th17 activity and severely reduced expression of IL-17.