John H Wolfe
Senior Member
- Messages
- 220
- Location
- London
Your poor family!My mother and cousin both have M.E .. My eldest daughter has it but not so far my other 3 children
Again, I wonder if there are any signs of innate anatomic abnormalities in your family e.g. misshapen spines, hypermobility, connective tissue disorders, or historic sources of environmental toxicity (including pre-natal, peri-natal) common to you and your daughter?
Also wonder whether she was breast fed?
For me that would depend on circumstances surrounding infection/reactivation (typically viruses like EBV are spread through saliva) and the neuroimmunological and inflammatory profile of the child in question (how well their system is able to cope)Surely if it was infectious all my children would have caught it when i was pregnant (apart from the 1st as i don’t think i had it then.)
Almost 100% of adults have evidence of previous infection of EBV so people whose family get sick with it, or similar viruses, really shouldn’t feel too guilty!
Around 80% of ME/CFS patients vs 20% of controls have gastro enteroviruses, which may cause problems if they travel up nerves. Certain gastro microbes may interact with viruses e.g. e.Faecalis vs. nerve based pathogens like EBVif there is a gut infection of some kind, and bacteria / toxins are going into the brain from the gut
For a while I flirted with the idea that ME/CFS may be to a certain extent rooted in gastrointestinal disorder. My current thinking is that gastrointestinal disorders and problems are secondary to a neurological aetiology (that may not, primarily, relate to infection at all)