I have 3 BHMT +/+ too, but I'm also COMT +/+ so I'm not sure what to do.
Me too. I also have 3 BHMT and COMT +/+ and COMT +/-. I take 2g TMG in divided doses with meals. The only things I do not take with meals are my hormone pills and antioxidants. Everything else could potentially hurt my stomach so I only take with food. I try to take my hormones and antioxidants when I first get up on an empty stomach, then the bulk of my pills at breakfast, then the few I take in divided dose I take later at lunch or dinner.
I don't take PS because it didn't seem to do anything for me. However I read this in Iron Man Magazine Feb 2013 about PS:
Researchers state that Ps can be used as a natural substitute for anabolic steroids.
The article says that cortisol is a muscle-melting hormone that floods your blood stream when you're stressd, such as when working out. This is why so many body builders who want to bulk up resort to steroids as tey partially block cortisol. Steroids bind with glucocorticoid cell receptors, those that interact with cortisol, and that tilts the balance away from muscle melting. [Hmm. Coffee = liquid cortisol. Also, DHEA is a steroid].
Studies show that PS taken orally can decrease cortisol 30%. There is even a book: Phosphatidylserine: Promise for Athletic Performance, by Edmund Burke PhD and Thomas Fahey Ed., D. They say that PS depressed cortisol production, while anabolic steroids block the action of cortisol by cross-linking with the cortico-steroid receptor site.
PS is entirely natural. It is a soy lipid often given to seniors to prevent muscle and brain degeneration.
As a result of PS lowering cortisol:
Lower cortisol levels have been shown to produce an increase in free testosterone and the more free t, the easier to build muscle. [More free t most likely means less DHT fyi]
PS has been shown to improve mental sharpness and focus.
Less cortisol reduces carb cravings and helps you drop fat. [This resonates...I have long learned that coffee increases carb cravings for me]
It makes me want to try PS again. The article does not discuss dose. The article is actually an ad for PS and the dose is presumably what they put in their supplement...