Thanks
@kangaSue ;
Magnesium used to work for me, but then it stopped and made constipation worse, insomnia too. Had it measured in blood, was highest normal. Usually it's because of a kidney problem, but I didn't have signs or symptoms.
I've read about low choline and low acetylcholine causing constipation, and we do seem to have an actetylcholine signalling issue here at PR.
For myself, the constipation looks to have an infectious cause, ( overgrowth of methanogens in intestines), and possibly other microbes.
Treating myself with abx has been the best intervention I've tried so far, and, how I've tried.
Many folks will benefit from magnesium, choline (maybe), etc., and I hope they do. It's a much simpler approach.