Marco
Grrrrrrr!
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- Near Cognac, France
Microglial activation/'neuroinflammation' is something of a hot topic in ME/CFS recently and many of us have neuropsychiatric symptoms such as anxiety/depression, cognitive issues etc.
Typical meds are far from lacking in side effects so it's interesting to find evidence of effectiveness of what appear to be fairly side effect free 'natural' (sic) substances.
It seems that Luteolin (contained in celery and chamomile for example) seems to be able to dampen down 'neuroinflammation' :
"We have shown that the flavonoid luteolin is a potent modulator of microglial activation, cell shape, and effector functions. Luteolin induced global changes in the transcriptome of resting or LPS-activated microglia leading to a polarized M2-like phenotype with anti-inflammatory and neuroprotective characteristics."
http://www.jneuroinflammation.com/content/7/1/3
Typical meds are far from lacking in side effects so it's interesting to find evidence of effectiveness of what appear to be fairly side effect free 'natural' (sic) substances.
It seems that Luteolin (contained in celery and chamomile for example) seems to be able to dampen down 'neuroinflammation' :
"We have shown that the flavonoid luteolin is a potent modulator of microglial activation, cell shape, and effector functions. Luteolin induced global changes in the transcriptome of resting or LPS-activated microglia leading to a polarized M2-like phenotype with anti-inflammatory and neuroprotective characteristics."
http://www.jneuroinflammation.com/content/7/1/3