Howdy there folks, so I am currently on round two of methylation therapy after trying a short trial run earlier this summer. The trial run involved Jarrow Methyl B12 Country Life Adeno B12, Solgar metafolin, Jarrow B complex (as per old recommendations of Freddd) L-carnitine, and coenzyme Q. I saw decent results with it, they were not life changing, but it did seem like my sleep was helped, and i slowly gained a little bit of energy. I hit a flatline rather quickly though, and when my supps ran out, I stopped, to see what would happen. I backslid the most on mood and sleep, but it was not that drastic. Decided to try this process again, with updated recommendations from freddd. I have been on round two for about a week now. Here is what i am taking: solgar metafolin (one tablet twice a day) Enzymatic Therapy Methyl b12 (one a day) Anabol Naturals Adeno B12 (one a day) Source naturals L-carn (one a day) Potassium support. I am not taking a multi due to folic acid content and no b complex. No coenzyme either. I have been on round two for one an a half weeks or so, and I am now having more disturbing side effects than I did the first time I tried this, and my overall level of health was better this time (confusing). Every time I use the Methyl B12, I get all or some of the following: My tinnitus cranks up, my hearing gets distorted, I get extremely cold, my eyes dry out, BP rises, my teeth grind, and lately, I have been getting very tired early in the day. These are all symptoms I have had in the past, but at separate times, in other words, I felt as they were resolved. I am extremely confused on why this second go around is giving me far more radical side effects than the first, especially since I have improved a little bit since then. I assumed some symptoms may be due to Potassium issues, so i have ramped up that intake plus Vit D, but I have increased food intake and am not gaining a single LB. I can take most of the symptoms save for the being cold and the extra tiredness, those have been extremely unpleasant. I want to continue through this if there is a definite upside, but not if I am causing myself to regress. I have not been as debilitated as some of you, and so I have much further to fall, so to speak. On the other hand, I have been seeing improvement in physical exertion (when not bone tired) and recovery. Mental clarity has been affected though, and I dont like that, as Brain Fog was not an original symptom of mine. Any Help?