Hi
@Freddd
Not sure if this is the correct place to ask about my issues with most supplements? It seems to be caused from overmethylation (breathing issues, jittery, feeling like I am going to explode) and histamine, gluten, salicylate and chemical sensitivity. This all started 3 years ago after 3 vaccines, 3 rounds of antibiotics, 10 days of NSAIDS and 3 month of mold exposure.
I hope you will help me shed some light on this? Like how to address the strange combo of overmethylation and histamine intolerance. I have seen so many peeps over the years ask this question in the forums, so I hope you - and maybe some other of the wise members - will join such an conversation. Not only for my sake, but also for others like me.
On the bright side - or maybe not
- I have done a lot of testing, so there is quite a lot of info to gain knowledge from - please ask for more if you can manage more.
Info:
Genes
I have several mutations that match my symptoms, like: 2 x COMT++ (over methylation), GSTP I105V+-, CYP2D6++, CYP2C9+-, CYP1B1++, 2 x CYP1A2+- (chemical sensitivity), and then: 3 x MTRR +-, MTR+-, 4 x NOS mutations, 2x SOD2 mutations, MAO A and B mutations, 11 x GAD+-, 3 x FUT++, 4 x NOS mutations (but ammonia is in range), CBS C699T +-
Amino, neurotransmitters, hormones etc
I am very low in methionine, homocysteine (DD-lab), cystatione, cysteine, gluthatione (according to OAT), serotonin, oestrogen, progesterone, DHEA, S-IgA.
GABA is within range because i supplement (according to GAD - and it takes away my tinnitus). T3 is in range because I supplement with pig thyroid hormone, so I am not quite as exhausted as I used to be.
I am high in taurine, citric acid (due to low gluthatione?), glycine, succinate.
Gut
I am low low in bifido and some important clostridia, but have corrected most issues (Ubiome testing)
Metal and toxic stuff
I have been following a diet that is without additives for 3 years, though not always organic (it is now). I have been a little high in lead, aluminium, tungsten, bismuth, arsenic, nickel, silver.
Diet
High protein low salicylate and low histamine paleo - high protein is to support methylation. When I was tested, I had just been through a periode, where I as under nourished (also in protein) due to intolerances - this might explain the low methionine etc?
Well.. hope you will find this interesting
Hugs Bibs