Thanks, Valentijn. Well, that's surprising to me based on my reaction when I added folinic acid to my regimen, but I made a lot of changes at once, so perhaps I need to isolate the change and try again. Hmmm, how would it complicate things for an MTHFR C677T mutation then, I wonder? If it's not depriving it of substrate, (which would affect more than C677T people), what could it be doing? Thanks. That was a good one, but that wasn't it. Maybe I confused or conflated something.