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In vitro evaluation of antiviral and virucidal activity of a high molecular weight hyaluronic acid

Discussion in 'Other Health News and Research' started by Gondwanaland, Aug 27, 2017.

  1. Gondwanaland

    Gondwanaland Senior Member

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    Free full paper
     
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  2. Gondwanaland

    Gondwanaland Senior Member

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  3. Hip

    Hip Senior Member

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    Hyaluronic acid is one of the enterovirus antiviral supplements and drugs listed on my post here.

    The issue, though, with in vitro studies like this one is that they tell you the concentration that produces a potent antiviral effect in a cell line in vitro experiment, but the study does not tell you whether this same concentration can be obtained in vivo, in the blood and tissues, when the compound is taken orally.

    If you can't obtain the same concentrations in the body, then you are not going to get any significant antiviral effect when you take the drug or supplement.

    Whether you can obtain the same concentrations as were used in the in vitro study depends on factors such as the oral absorption and bioavailability of the drug or supplement. If the bioavailability is poor, then you may not be able to get high enough levels in the blood and tissues.
     
    Last edited: Aug 27, 2017
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  4. Gondwanaland

    Gondwanaland Senior Member

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