being scared of all the big doses of folate that some people are mentioning in this thread, I would like to ask a question. Lets say that someone uses 800mcg of mfolate for start up and then start up indeed happens then when the first set back happends you realise that this person needs to raise the dose of mfolate in order to control the paradoxial defeciency symptoms. However in order to do that he needs to triple the dose and not just go from 800mcg to 1000mcg. Lets say 2400mcg are enough for him to control the symptoms. Is there any person stayed there and that dose was sufficient for him to control the symptoms, or everyone here need to constantly increase their mfolate doses?