I recently started a basic methylation protocol as I try to recover from a damaged liver and the oxidative stress that accompanies this. It was working great for a couple weeks @ methylcobalamin-1g and 800mcg l-methylfolate. Started seeing life a lot more clearly, and my libido improved.
All of a sudden in the last week however I have hit a major depression. I have never felt like this in my entire life but its a deep depression. I have been trying to push friends and family away suddenly as I seek complete isolation. And I'm paranoid about situations that probably aren't happening. My libido has tanked as well...
I thought perhaps I was over-methylated but everything I read suggests adding l-methylfolate to fix this and by adding more l-methylfolate it actually makes the situation worse. I've tried adding more donors including zinc, p5p, TMG, even SAM-E. Nothing is really helping...
Today I've stopped folate to try and level myself out again, so far no better off.
What could this be? Over-methylation? Methyl-trapping? Low B12? Emotions from toxins leaving the liver? (I have a messed up liver due to genetics/accutane - 15 flushes in with significant results)
All of a sudden in the last week however I have hit a major depression. I have never felt like this in my entire life but its a deep depression. I have been trying to push friends and family away suddenly as I seek complete isolation. And I'm paranoid about situations that probably aren't happening. My libido has tanked as well...
I thought perhaps I was over-methylated but everything I read suggests adding l-methylfolate to fix this and by adding more l-methylfolate it actually makes the situation worse. I've tried adding more donors including zinc, p5p, TMG, even SAM-E. Nothing is really helping...
Today I've stopped folate to try and level myself out again, so far no better off.
What could this be? Over-methylation? Methyl-trapping? Low B12? Emotions from toxins leaving the liver? (I have a messed up liver due to genetics/accutane - 15 flushes in with significant results)