Lipkin's Monster ME/CFS Study: Microbes, Immunity & Big Data
The Microbe Discovery Project outlines an ambitious new study by top researchers that has collected patient samples, but needs desperately funds to complete the work.
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CFI Spinal Fluid study from Lipkin and Hornig is out.

Discussion in 'Latest ME/CFS Research' started by aimossy, Mar 31, 2015.

  1. MeSci

    MeSci ME/CFS since 1995; activity level 6?

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    Avoiding pricks tends to be a good idea. Difficult when you have ME - or Lyme by the look of it. :lol:
     
    Battery Muncher, NK17 and duncan like this.
  2. NK17

    NK17 Senior Member

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    @duncan and @MeSci can you please help me locate where in this thread you/we started talking about Lyme in regards/connection to the Hornig and Lipkin CSF study and the rationale?

    I'm in a big crash and have to conserve the little energy I have for other daily living activities.

    Thanks
     
  3. duncan

    duncan Senior Member

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    Sure, NK17. Check over midway on page 12 I think. There wasn't much rational other than the flow just trended in that direction.
     
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  4. NK17

    NK17 Senior Member

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    I really appreciate your help @duncan
    TY
     
  5. MeSci

    MeSci ME/CFS since 1995; activity level 6?

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    There are lots of references to Lyme in the thread. You can find them using the standard PR search facility - just type in 'lyme' and select 'search this thread only'. This is the first mention I found that way.
     
  6. NK17

    NK17 Senior Member

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    TY
     
  7. worldbackwards

    worldbackwards A unique snowflake

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    Just an abstract, unless anyone has access:

    http://www.nature.com/mp/journal/v21/n2/full/mp201529a.html
     
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  8. A.B.

    A.B. Senior Member

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    That doesn't sound subtle at all.
     
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  9. Marky90

    Marky90 Science breeds knowledge, opinion breeds ignorance

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    "Our results indicate a markedly disturbed immune signature in the cerebrospinal fluid of cases that is consistent with immune activation in the central nervous system, and a shift toward an allergic or T helper type-2 pattern associated with autoimmunity." - Sexy.
     
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  10. John Mac

    John Mac Senior Member

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    Liverpool UK
  11. FancyMyBlood

    FancyMyBlood Senior Member

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    John Mac likes this.
  12. shannah

    shannah Senior Member

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    Wonder why it was published in Molecular Psychiatry rather than an Immunology journal.
     
  13. rosie26

    rosie26 Senior Member

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    This allergic component was exciting to me as well when I read it. I will be interested in just what this is and it's affects and how they relate - it's been quite serious for me this last year and it's got to a level of feeling quite destructive.
     
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  14. Marky90

    Marky90 Science breeds knowledge, opinion breeds ignorance

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    Yep! I read somewhere that there is a higher portion of allergies in ME-patients compared to controls, fits with me as i have a big allergy towards grass.
     
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  15. adreno

    adreno PR activist

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    Allergic here, too.
     
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  16. Snowdrop

    Snowdrop Rebel without a biscuit

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    Started with the usual allergies to grass pollen etc years ago and have graduated to more and different allergies--my cats, some foods.
    Although none of these are serious so far only mild to moderate.

    I get the impression though that allergies aren't all that uncommon in the general (and otherwise healthy) population.
    And although I do have allergies I have never considered them anything like a main symptom until recently they seem to be moving up the queue.
     
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  17. Marky90

    Marky90 Science breeds knowledge, opinion breeds ignorance

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  18. Forbin

    Forbin Senior Member

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    Last edited: Jan 20, 2016
    John Mac likes this.
  19. roller

    roller wiggle jiggle

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    TH2 ???
    who would this fit with the virus-theory causing CFS ME?

    virus and bacteria cause TH1+
    worms and allergies cause TH2+

    however, worms/allergies come along with bacteria/viruses as well.
     
  20. Kina

    Kina

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    Please note:

    The posts starting at post 306 and ending with 319 were originally in the thread titled 'New Hornig/Lipkin paper in Molecular Psychiatry'. The posts were merged into this thread as they both are about the same study.

    Thank you.
    :)
     
    Last edited: Jan 21, 2016

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