Based on Nos. 65-68, it sounds like it measures titer of viral load, too, right? So when they start testing antiretrovirals, theyll be able to check that its working by the viral load?
Has anybody seen this (from )?
McCormick et al. recently explored the candidacy of XMRV in ALS; however, they did not find XMRV in the blood or CSF of the 25 ALS patients where reverse transcriptase (RT) was detected (McCormick, A. L., et al., Neurology 70: 278, 2008).
The present inventors have developed and disclose herein methods of detecting antibody against the gammaretrovirus Xenotropic Murine Leukemia Virus-Related Virus (XMRV) in a subject. Furthermore, the present inventors have established that a diagnosis of a neurological disease such as a neuroimmune disease, or a lymphoma in a subject can correlate with infection with XMRV. In various aspects, a subject can be a person having, suspected of having, or at risk for developing an XMRV-related disease.
I wonder if they have looked for XMRV in all of these diseases yet (Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia lymphoma, Niemann-Pick Type C Disease, fibromyalgia, Multiple Sclerosis (MS), Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS) and autism)? Are they testing Parkinsons patients even as we wait for publication of an ME/CFS replication study? Gee, wouldnt it be something if this one retrovirus could be a significant clue to the pathogenesis of all these diseases?
Im surprised it doesnt mention Gulf War Syndrome.
Accordingly, in various embodiments of the present teachings, detection and/or quantification of antibodies against XMRV in a subject can be used to diagnose an XMRV-related disease, monitor progress of an XMRV-related disease, or determine efficacy of a treatment of an XMRV-related disease in a subject.