XMRV in autism: thoughts


Senior Member

Detection of infectious XMRV in the peripheral blood of children


Hi everybody,

Im sure you have already discussed about this study, but I am unable of checking the whole forum

Just wanted to express my reflection: an 82% of autistic children being XMRV+, is what would be expected if, indeed, XMRV is playing a vital role in the pathogenesis or perpetuation of CFS, because, as Rich Van A. Konynenburg has pointed out in his work on CFS, both conditions are highly similarBoth show a methylation cycle block that perfectly well could be the biochemical core explaining most of the features of each disorder. Also both conditions show similar immune dysfunction profile, mitochondrial failure, etc.

Id like to recall that methylation, very probably is (not sure if this has been published for XMRV yet) the main mechanism of genetic silencing needed to avoid the expression of XMRV (as occurs for VIH and other chronic infections, if not for all of them).

Coincidence? Maybe, as this is not ruling out the possibility of XMRV being just a secondary infection in both conditionsBut, I am glad to see this results, as the opposite wouldnt have matched with XMRV being important in CFS