Serrapeptase would definitely be worth trying. I'm going to start with it and work my way through a few different proteolytic enzymes, such as nattokinase, sepose, lumbrokinase. They all work a little different and I think serrapeptadase has the lowest molecular weight which I think would cause the least side effects. I think Nattokinase and Lumbrokinase are the strongest against Biofilms, but can be a little overwhelming if the dose is to high.