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Woman warns against Gardasil vaccination (says caused CFS) (Australia)

Dolphin

Senior Member
Messages
17,567
(I had a quick look around and couldn't see this story or indeed a similar thread)

http://express-advocate-wyong.whereilive.com.au/news/story/woman-warns-against-gardasil-vaccination/

MOTHER of three Lyndsey Bourne has a message for young women - investigate before you vaccinate.

Ms Bourne, of Erina, suffers chronic fatigue syndrome and is convinced her condition is a reaction to Gardasil, a vaccination against cervical cancer.

The vaccination, an Australian first, was designed to protect against the second biggest cause of female deaths from cancer and is available free to women under 26.

etc
 

Carrigon

Senior Member
Messages
808
Location
PA, USA
Those shots were never safe. Alot of women died from those already. It's very scary. And they still haven't taken it off the market yet.
 

SOC

Senior Member
Messages
7,849
IMO, the issue with this vaccine is that it's a live-virus vaccine. At present we are avoiding live-virus vaccines because of major relapses from previous ones. We do get killed-virus vaccines without serious problems.

The advice we got from 2 different ME/CFS specialists about Gardasil is that because it is a live-virus vaccine, our daughter should avoid taking it as long as she is not exposing herself to the virus. Both gave us something along the lines of "we'll decide when we get there" when asked what a sexually active woman with ME/CFS should do about Gardasil.

This is a valuable vaccine that can protect women from serious illnesses. I, personally, wouldn't avoid it because of internet scare stories. I think young women with ME/CFS have some tough decisions to make about Gardasil. While doctors are encouraged to give the vaccine to every female between 10 and 26yo, I think we need to give it more individual consideration which should include a careful and honest discussion with an ME/CFS-savvy doctor.
 

SOC

Senior Member
Messages
7,849
Actually, it is a recombinant vaccine. It is not meant to contain any viral DNA. It is meant to contain virion like particles with the antigenic proteins in tact.

Thanks for the info. Now if I only knew what it meant. :D I only know what the docs told me, and I was kinda stuck trusting it because I don't have any medical training.

Can you explain to me how this type of vaccine would impact the immune system? My impression (quite possibly wrong, of course) was that "killed virus vaccines" could not replicate, while "live virus vaccines" could, which was the problem. From your description it sounds like this recombinant vaccine could not replicate, which would put in closer to the "killed virus vaccine" in this context, and therefore less of a risk. Is that right?
 

free at last

Senior Member
Messages
697
I lost the link where a newspaper ran a story about british girls who had this vaccine, and developed cfs symptoms,my daughter was due to have her shot at school, but im refusing it for two reasons, the concerns im reading about it, and the fact im xmrv positive,seems to be a double danger of concern there. when shes older they may develop a safer vaccine, and we may know more about xmrv or if shes also positive. the link with cfs symptoms seems small but not non existent.wonder if the vaccine is activating xmrv positive girls.giving girls xmrv,or some other problem leading to cfs, in a tiny proportion
 

wdb

Senior Member
Messages
1,392
Location
London
So one of 40 odd million doses happens to coincide with the CFS onset in one person. This is not evidence this is sensationalist nonsense.

Safety

As of February 2009, 40 million doses of Gardasil had been distributed worldwide.[37] The vaccine was tested in thousands of females (ages 9 to 26).[38] The Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) consider the vaccine to be safe. It does not contain mercury, thiomersal or live virus or dead virus, only virus-like particles, which cannot reproduce in the human body.[38]

The FDA and the CDC say that the vaccine has only minor side effects, such as soreness around the injection area.[38] Fainting is more common among adolescents receiving the Gardasil vaccine than in other kinds of vaccinations. Patients should remain seated for 15 minutes after they receive the HPV vaccine.[39] There have been reports that the shot is more painful than other common vaccines, and the manufacturer Merck partly attributes this to the virus-like particles within the vaccine.[40] General side effects of the shot may include joint and muscle pain, fatigue, physical weakness and general malaise.[41]

An update on adverse events was published by JAMA and looked at data from the Vaccine Adverse Event Reporting System (VAERS), covering 12,424 reported adverse events after about 23 million doses of vaccine between June 2006 and December 2008.[42][43] Most adverse effects were minor and not greater than background rates compared with other vaccines, the exception being higher rates for syncope and venous thromboembolic events.[43] Venous thromboembolic events were noted in 56 reports at a rate of 0.2 cases per 100,000 doses distributed and included 19 cases of pulmonary embolism, 4 of which were fatal.[43] Overall, 772 events (6.2% of the total number of adverse events, but only 0.003% of the total number of doses) were described as serious and included 32 deaths (1 per 1,000,000 doses).[43]
Other adverse events include local site reactions (7.5 cases per 100,000 doses distributed), headaches (4.1 cases per 100,000 doses distributed), hypersensitivity reactions (3.1 cases per 100,000 doses distributed), and urticaria (hives) (2.6 cases per 100,000 doses distributed).[43]

The FDA and the CDC said that with millions of vaccinations "by chance alone some serious adverse effects and deaths" will occur in the time period following vaccination, but have nothing to do with the vaccine.[44] More than 20 women who received the Gardasil vaccine have died, but these deaths have not been causally connected to the shot.[44] Where information has been available, the cause of death was explained by other factors.[45][46] Likewise, a small number of cases of Guillain-Barr Syndrome (GBS) have been reported following vaccination with Gardasil, there is no evidence linking GBS to the vaccine.[12][47][42] It is unknown why a person contracts GBS, or what initiates the disease.[48]

The FDA and the CDC monitor events to see if there are patterns, or more serious events than would be expected from chance alone.[45] The majority (68%) of side effects data were reported by the manufacturer, but in about 90% of the manufacturer reported events, no follow-up information was given that would be useful to investigate the event further.[43] In February 2009, the Spanish ministry of health suspended use of one batch of Gardasil after health authorities in the Valencia region reported that two girls had become ill after receiving the injection. Merck has stated that there was no evidence Gardasil was responsible for the two illnesses.[37]
 

free at last

Senior Member
Messages
697
So one of 40 odd million doses happens to coincide with the CFS onset in one person. This is not evidence this is sensationalist nonsense.

Safety

As of February 2009, 40 million doses of Gardasil had been distributed worldwide.[37] The vaccine was tested in thousands of females (ages 9 to 26).[38] The Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) consider the vaccine to be safe. It does not contain mercury, thiomersal or live virus or dead virus, only virus-like particles, which cannot reproduce in the human body.[38]

The FDA and the CDC say that the vaccine has only minor side effects, such as soreness around the injection area.[38] Fainting is more common among adolescents receiving the Gardasil vaccine than in other kinds of vaccinations. Patients should remain seated for 15 minutes after they receive the HPV vaccine.[39] There have been reports that the shot is more painful than other common vaccines, and the manufacturer Merck partly attributes this to the virus-like particles within the vaccine.[40] General side effects of the shot may include joint and muscle pain, fatigue, physical weakness and general malaise.[41]

An update on adverse events was published by JAMA and looked at data from the Vaccine Adverse Event Reporting System (VAERS), covering 12,424 reported adverse events after about 23 million doses of vaccine between June 2006 and December 2008.[42][43] Most adverse effects were minor and not greater than background rates compared with other vaccines, the exception being higher rates for syncope and venous thromboembolic events.[43] Venous thromboembolic events were noted in 56 reports at a rate of 0.2 cases per 100,000 doses distributed and included 19 cases of pulmonary embolism, 4 of which were fatal.[43] Overall, 772 events (6.2% of the total number of adverse events, but only 0.003% of the total number of doses) were described as serious and included 32 deaths (1 per 1,000,000 doses).[43]
Other adverse events include local site reactions (7.5 cases per 100,000 doses distributed), headaches (4.1 cases per 100,000 doses distributed), hypersensitivity reactions (3.1 cases per 100,000 doses distributed), and urticaria (hives) (2.6 cases per 100,000 doses distributed).[43]

The FDA and the CDC said that with millions of vaccinations "by chance alone some serious adverse effects and deaths" will occur in the time period following vaccination, but have nothing to do with the vaccine.[44] More than 20 women who received the Gardasil vaccine have died, but these deaths have not been causally connected to the shot.[44] Where information has been available, the cause of death was explained by other factors.[45][46] Likewise, a small number of cases of Guillain-Barr Syndrome (GBS) have been reported following vaccination with Gardasil, there is no evidence linking GBS to the vaccine.[12][47][42] It is unknown why a person contracts GBS, or what initiates the disease.[48]

The FDA and the CDC monitor events to see if there are patterns, or more serious events than would be expected from chance alone.[45] The majority (68%) of side effects data were reported by the manufacturer, but in about 90% of the manufacturer reported events, no follow-up information was given that would be useful to investigate the event further.[43] In February 2009, the Spanish ministry of health suspended use of one batch of Gardasil after health authorities in the Valencia region reported that two girls had become ill after receiving the injection. Merck has stated that there was no evidence Gardasil was responsible for the two illnesses.[37]

Well the 1 in 40 million happening to coincide with cfs statement is absolutely wrong, as i was reading about 3 girls in the uk ALONE who developed cfs symptoms soon after the vaccine NOT TWO YEARS LATER ( Just happen to coincide ? seems doubtfull ) also the effect of certain vaccines on xmrv positive people is very uncertain at the moment, The cases of sophia mirza and Lynn Gilderdale both sever ME after vaccine one Soon after, the other not so soon after, i wonder if sophia and lynn were xmrv positive, who knows. But the point is much is uncertain about all these things. i think my lil girl has few years at least untill i will need to examine the evidence of both xmrv and vaccine connections, or just this particular vaccine safety.Im certainly not saying the vaccine might not be warrented, just that for me personally i have a little time to see how these things pan out. i wont use her health lightly, i just wont do it.
 

Snow Leopard

Hibernating
Messages
5,902
Location
South Australia
Thanks for the info. Now if I only knew what it meant. :D I only know what the docs told me, and I was kinda stuck trusting it because I don't have any medical training.

Don't take personal offence, besides you made it clear that it was advice that you were given.

The proteins are typically expressed in bacteria or yeast, through the use of DNA recombination technology. Since it is a biological process it means that the quality of the output is not guaranteed 100% identical. There is also a (very small) chance of contamination, as with any biotech product.

I wasn't sure of the details of Gardasil, but it is made by producing the capsid protien in yeast through recombinant technology. The capsid is basically the main structural "shell" protein. But most viruses are then covered with a lipid membrane, squired from the budding from a cell wall (which is also covered with a lipid membrane), however HPV is a non-enveloped virus.

Can you explain to me how this type of vaccine would impact the immune system? My impression (quite possibly wrong, of course) was that "killed virus vaccines" could not replicate, while "live virus vaccines" could, which was the problem. From your description it sounds like this recombinant vaccine could not replicate, which would put in closer to the "killed virus vaccine" in this context, and therefore less of a risk. Is that right?

What can go wrong in a biological system? A lot. There can be anything from allergic reactions, to weird recombination of the antigens with other human proteins, causing weird immune reactions and even autoimmunity.

I know there is a lot of hype about HPV and the cancer risk. But the amount of serious adverse reactions from the vaccination (if you read the published studies) is in the same ballpark as the number of women who are diagnosed with cervical cancer per year in the USA (at least those likely to be due to the virus). But who is to say that this virus doesn't cause other health risks? Maybe it even could contribute to CFS? Biology has always had more questions than answers.

I personally developed CFS less than a week after a dose of the oral polio vaccine (live attenuated) and DPT (toxoid vaccine, since they are bacteria). I was of course investigated for Guillain-Barr Syndrome, but neurologists didn't find much. Do you think my case was further investigated as a 'vaccine injury'? The answer is no.
 

3CFIDS@ourhouse

still me
Messages
126
Location
Southeast US
The Gardisil vaccination contains a form of aluminum as an adjuvant, as do many other vaccines. Russell Blaylock, a neurologist (a very controversial neurologist, granted) has this to say about aluminum.

"In fact, we know that aluminum is a significant neurotoxin and that it shares many common mechanisms with mercury as a neurotoxin. For example:

- They are both toxic to neuronal neurotubules.
- Interfere with antioxidant enzymes.
- Poison DNA repair enzymes.
- Interfere with mitochondrial energy production.
- Block the glutamate reuptake proteins (GLT-1 and GLAST).
- Bind to DNA.
- Interfere with neuronal membrane function. "

Someone recently listed this source of vaccine information, but I think it's worth mentioning again. en.wikipedia.org/wiki/List_of_vaccine_ingredients