Hi knackers. I think it must have to do w/ the antibodies crated by gluten and dairy. Before I stumbled upon the GAPS diet I was ready to end my life. My nervous system was so overactive, that life was unbearable. By mid 2011 I thought I had a brain tumor. I'd been able to improve my situation a bit by adding glandular supplements: hypothalamus, adrenal, pituitary. The hypothalamus, within 3 hours, stopped my extreme stress reactions. Prior to this, when I went out into the heat, which wasn't objectively terribly hot, I began hyperventilating and shaking. This was also my response to any extreme noises, like blowers, chain saws, and had been for a year. I was an agony of nervous excitation. 3 days into the gluten/dairy-free diet, my nervous system calmed. By the 2 week mark, the remaining Dupuytrens Contractures in my hands, and residual frozen shoulder released. Over the following year I uncovered pyroluria, which includes connective tissue issues, as being a factor for me, and supplemented for it, bringing many more benefits. These supps included minerals, p5p, and TMG: a methyl donor! I now believe pyroluria, discovered before genetic testing, to be a condition common in MTHFR and CBS mutations.
Also I forgot to include in my response about my improvements, that in the last months I've regrown the hair on my arms and legs, and I'm no longer overheating. I can tolerate warm weather again, which had been a terrible stressor for me in the last couple years before finding GAPS, then getting the whole methylation pathway working. I've also reduced my thyroid doses from 60 to 40 mcg. It's funny, I've kept such track of my symptoms over these years, and yet now, when I'm truly healing, I have to think hard to remember some of the drastic things I've now recovered from. cheers, ahmo