ChookityPop
Senior Member
- Messages
- 563
I found these but I dont know if its optimal.
Hallmarks of T Cell Exhaustion
Hallmarks of T Cell Exhaustion
- Co-express multiple inhibitory receptors: PD-1, CTLA-4, LAG-3, TIM-3, 2B4/CD244/SLAMF4, CD160, TIGIT.
- Loss of IL-2 production, proliferative capacity, ex vivo cytolytic activity.
- Impairment in the production of TNF-alpha, IFN-gamma, and cc (beta) chemokines.
- and the recently described B- and T-lymphocyte attenuator (BTLA).