like @cigna and others, I find this hypotheses very intriguing. i've always been struck by the "hypersensitivity" aspect of ME/CFS. Off the top of my head I can think of hypersensitivities to mold, various types of food, sound, light, temperature, odors, exertion, and a few more....
@Jonathan Edwards, what do you mean by "anything would show up"? Do you mean no elevated antibody levels?