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Vitamin D

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Has anyone encountered research on what might cause low Vitamin D in ME/CFS?

My Vit. D is very low. What is the most effective way to increase Vit. D? I get a lot of sun exposure, but my gut is horrible. If I take a supplement in capsule form (not a spray), will my gut problems affect the absorption of it?

Thanks,
Matt
 

wabi-sabi

Senior Member
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Has your doc recommended you a dose? I was tested and then was given a dosage based on my blood level. Seems to have done the trick on retesting, since I came up to normal. On the other hand, it doesn't make any difference to how I feel.
 

Wolfcub

Moderator
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Yes I think certain gut conditions can affect the absorption of vitamin D supplements.
Stomach juices, pancreatic secretions, bile from the liver, the integrity of the wall of the intestine — they all have some influence on how much of the vitamin is absorbed. Therefore, conditions that affect the gut and digestion, like celiac disease, chronic pancreatitis, Crohn's disease, and cystic fibrosis, can reduce vitamin D absorption.
Quoted from this webpage: https://www.health.harvard.edu/healthbeat/9-things-that-can-undermine-your-vitamin-d-level

The solution may be to take a little more? Check that idea with the doctor.
 

kangaSue

Senior Member
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Gut problems can be a catch 22 issue where vitamin D is concerned;
https://www.ncbi.nlm.nih.gov/pubmed/27515213 Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid adversely affects the immune system, producing a "pro-inflammatory" state associated with atherosclerosis and autoimmunity. (2016)

You can get megadose intramuscular injections of cholecalciferol (anything from 200,000 to 600,000iu).
https://www.mja.com.au/journal/2005...-megadose-cholecalciferol-treatment-vitamin-d