Thanks very much for the links, Frank.
Best quote (from Hyde): "You can do a lot with half a brain!"
I didn't expect Hyde to be so soft-spoken, but man did he take a swipe at WPI! "Contamination", "advertising"... harsh. This was from November, from the same trip where he made his other well-known remarks, and I wonder if he's softened his position since then (though I kind of doubt it).
Also surprised to hear he doesn't treat at ALL, and sends patients out to specialists for treatment of diagnosed pathologies (I hope he coordinates and advises about those specialists' treatment recommendations, at least). He's one of the real good guys and was there at the genesis of the CFS mess (see Osler's Web, etc), but he's definitely very hard-assed, realpolitik in his views. (And he pretty much admits this.) Definitely a unique, and valid, approach, though he doesn't seem as interested in immune dysfunction as many others. My sense from reading what I could of his own writings is that he is a strict clinician, and forms his model based more on intense clinical evaluations of patients than on hypotheses drawn from research.
Interesting also about the shrinking thyroid glands he mentions so prominently. I knew he had mentioned them before, but not in great detail.. Now how in the world am I gonna get THAT test done..
!! A bit weird to hear him recommending thyroid supplements a la Teitelbaum et al (to some extent).
As for DeMeirleir...
, I understood DeMeirleir to be saying that he knew from DeFreitas' work that a retrovirus was somehow involved in some patients, though he may not have been aware at the time of this interview that the WPI feels this is a different retrovirus. His position on XMRV may have changed since this interview, too. I believe here he was saying that XMRV may play a key role in a subset of ME cases, but not in all, so in that sense it is only a "piece of the [overall] puzzle".
Does anyone know if the big H2S study (300 patients) DeMeirleir mentioned in this interview has been published yet? Too zonked to go searching just now..