Vanderbilt Recruiting CFS + POTS Patients for Study

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Purpose

The investigators propose to test the hypothesis that the sympathetic nervous system contributes to the cardiovascular and inflammatory abnormalities present in the chronic fatigue syndrome (CFS) and, in particular in the subset of patients characterized by postural tachycardia syndrome (POTS). CFS and POTS are seen mostly in otherwise normal young women, and are the cause of significant disability. A substantial proportion of patients referred for evaluation of POTS met diagnostic criteria for CFS and, conversely, a subset of patients referred for treatment for CFS have POTS. The investigators hypothesize that sympathetic activation underlies the pathophysiology of patients in whom CFS and POTS overlap (CFS-P).
More Information at link;

http://clinicaltrials.gov/ct2/show/NCT00580619
 

ramakentesh

Senior Member
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In this study they will be trialling methyldopa to decrease sympathetic drive.
The theory being that the decreased blood flow to the brain in CFS/POTS is a result of failing cerebral vascular autoregulation from an increased sympathetic activity.
 
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I'd love to know too if anyone has gotten in to this study. Fairlight, good luck with the droxidopa, hope you can get it. Please let us know how you do.