Here you go. Better read the disclaimer.
https://trueterpenes.com/products/pure-terpene-isolates/isolates/beta-caryophyllene/
People are different sizes and have different genetics which affect if and how drugs work as well as dosing needed for benefit. It's not a one size fits all thing.
A lot of ME/CFS patients can only tolerate tiny doses and have magnified effects from normal doses.
So, how are you going to safely take it? Seems like vaping it is a bad idea... How does one ne know the exact concentration and dose?
UNII - BHW853AU9H (fda.gov)
beta-Caryophyllene | C15H24 - PubChem (nih.gov)
People are different sizes and have different genetics which affect if and how drugs work as well as dosing needed for benefit. It's not a one size fits all thing.
Thats why I said it had to be the right dose?
Everyone has cannabinoid receptors and they do the same thing in everyone. This works on mechanistic principles of receptor and ligand, equals effect X against mechanism Y.
A lot of ME/CFS patients can only tolerate tiny doses and have magnified effects from normal doses.
I thought you might say that, but I am sure my point that I was making did not completely pass you by?
So, how are you going to safely take it? Seems like
vaping it is a bad idea... How does one ne know the exact concentration and dose?
I have consumed this in cannabis in smaller amounts over a 25 year period until I discovered what it was and found a source of higher concentration and started to consume that.
I have been vaping it and have been since the first time I tried Copaiba essential oil, which funny enough is used on diffusers in aroma therapy, so you breath it in.
I have also made a sublingual dropper with it and put it in gelatine capsules.
I now do not have any symptoms 99% of the time when I keep up with the Copaiba.
Caryophyllene /ˌkærioʊˈfɪliːn/, more formally
(−)-β-caryophyllene,
(BCP), is a natural bicyclic
sesquiterpene that is a constituent of many
essential oils, especially clove oil, the oil from the stems and flowers of
Syzygium aromaticum (cloves),
[3] the essential oil of
Cannabis sativa,
rosemary,
[4] and
hops.
[5] It is usually found as a mixture with isocaryophyllene (the
cis double bond isomer) and
α-humulene (obsolete name: α-caryophyllene), a ring-opened isomer. Caryophyllene is notable for having a
cyclobutane ring, as well as a
trans-double bond in a 9-membered ring, both rarities in nature.
Caryophyllene is one of the chemical compounds that contributes to the
aroma of
black pepper.
[12]
Caryophyllene has been given GRAS (generally regarded as safe) designation by the FDA and is approved by the FDA for use as a food additive, typically for flavoring.
[13][14]
Caryophyllene oxide,
[17] in which the
alkene group of caryophyllene has become an
epoxide, is the component responsible for cannabis identification by
drug-sniffing dogs[18][19] and is also an approved food additive, often as flavoring.
[14]
This is from the manufacturer in India of what I use-
View attachment 1657100980791.png
Copaiba
The
balsam may be
steam distilled to give
copaiba oil, a colorless to light yellow liquid with the characteristic odor of the balsam and an aromatic, slightly bitter, pungent taste. The oil consists primarily of
sesquiterpene hydrocarbons; its main component is
β-caryophyllene.
[1] The oil also contains significant amounts of
α-bergamotene,
α-copaene, and
β-bisabolene.
[2]
Copaiba oil-resins extracted have been used in
folk medicine dating back to the 16th century by the natives of north and northeastern Brazil. The folk remedies were administered orally or used as an ointment in the treatment of various diseases.
[5] In Panama, the Yaviza people mix the resin with
honey and give it to newborns to impart knowledge and ward off hexes.
[6] Within the Peruvian Amazon near Iquitos, it is also used as an insect repellent.
Industry and commerce
The production of copaiba oil is socially significant to the
Amazon because it represents approximately 95% of Brazil's oil-resin production industry. The Annual production of copaiba oil in the Amazon is estimated to be 500 tons/year.
[7] The commercialization of copaiba as an oil or in capsule form has grown because of demand by traditional and widespread use, and is exported to other countries, including the
United States,
France, and
Germany.
[8]
The Food and Chemicals Codex lists copaiba oil as safe as a flavoring agent for foods.
[9] Copaiba oil has both an acute oral and dermal
LD50 exceeding 5 g/kg,
[10] which classifies it as non-toxic.
[11]
I hope that answers your questions
