Thymosin Alpha 1

[Learner1]

Thanks for your input, I appreciate it! You are a warrior my friend! I will read more about it and call my doctor tomorrow and get it.

I just found this article today, which supports why it might be useful in ME/CFS - we are known to have oxidative and nitrosative stress...

 

[ChookityPop]

I just found this article today, which supports why it might be useful in ME/CFS - we are known to have oxidative and nitrosative stress...

Interesting! How are you dosing? 0.3mg before bed? How long before bed?

 

[Wendi C]

Can I ask where you order your Epithalon?

PeptideSciences.com

 

[Learner1]

PeptideSciences.com

So, are you a researcher? It says you can only buy their products if you're a researcher... How do you buy them?

 

[ChookityPop]

anyone have experiences taking peptides during PEM? I felt amazing on bpc 157, then I had to stop because my order with new bpc took forever. Started Thymosin Alpha 1, felt good. Havent had any issues with birch pollen all may. Very interesting. a week ago I started a new cycle of bpc 157 (different source) simultaniously with me getting a PEM first time in months. I have had lots of sex with a new partner and took it too long I guess.. I am super tired and feel nauseous after ta1 or after eating. I dont know what made me nauseous.

Getting tb500 later today for the first time and I am excited. Should I wait til the PEM resolves or just go for it? Anyone with similair experience during PEM with peptides?

 

[Wendi C]

No - you do not have to be a researcher. I'm sure that statement is there to cover them legally. Purchasing more today. You can pay by Venmo, Zelle, E-check..

So, are you a researcher? It says you can only buy their products if you're a researcher... How do you buy them?[/QUOTE

 

[mitoMAN]

Did anyone find a retailer that ships Thymsoin Alpha 1 to EUROPE from inside the EU or UK?

Sadly German customs are very very aggressive and strict, and I heard of people having legal problems with importing peptides from the US already.
I am stuck in Germany during Corona and might give it a try once I move back to Austria. Customs there are less strict.

 

[ChookityPop]

Gammanorm together with Ta1?
Ive been thinking about trying Gammanorm which is supposed to boost the immune system together with Thymosin Alpha-1. Both the boosting and regulating qualities of these would be interesting to try over a longer period. What do you guys think? Anyone tried this combo

I would also appreciate a legit source for TA1 inside europe.

 

[mitoMAN]

Gammanorm together with Ta1?
Ive been thinking about trying Gammanorm which is supposed to boost the immune system together with Thymosin Alpha-1. Both the boosting and regulating qualities of these would be interesting to try over a longer period. What do you guys think? Anyone tried this combo

I would also appreciate a legit source for TA1 inside europe.

I just ordered from the only source I could find - looked everywhere. but TA-1 is rare!
https://pharmalabglobal.com/product/thymosin-alpha-1-10mg-vial/

shipping from UK


I ordered TB-500 and BPC-157 from Trident Peptide UK
and
Thymosin Alpha-1, LL-37 and Epitalon from Pharmalabglobal.com

I will probably first start with adding TB-500 and LL-37 to my existing BPC-157 stack to try and heal my gut issues.

After a month I might try starting TA-1 and keep u guys updated ofcourse.

 

[mitoMAN]

Also: Anyone found out the difference between Thymosin Alpha 1 and
Thymalin
yet?

 

[ChookityPop]

After a month I might try starting TA-1 and keep u guys updated ofcourse.[/QUOTE]

Nice, keep us posted! https://direct-peptides.com/product/thymosin-alpha-1-peptide-vial-copy/ This is another source, I havent tried it though. Anyone else used direct peptides?

 

[mitoMAN]

I started Thymosin Alpha-1 today. 330mcg
After the shot I felt kind of dizzy and a bit sick for the next 8 hours. (Like mildly wanting to vomit)

10 days in with TB-500 500mcg daily and still using BPC-157 500mcg since May.
But no real success with BPC-157 alone. Maybe things will change with TA-1 and TB-500 in the mix now.


Just wondering, did you hear any feedback if there is a difference in taking twice weekly injections of TA-1 and TB-500 contrary to smaller dosages daily? These have long halflifes - so many peptide companies suggest taking it 2-3 times per week instead of daily.

Sometimes, "huge dosages 1-2 weekly" will have different impact than small dosages daily. Cant find much information on it tho.

 

[ChookityPop]

These have long halflifes - so many peptide companies suggest taking it 2-3 times per week instead of daily.

I know Thymosin alpha 1 has 2 hours half life, thats super short. Would it be ideal to inject multiple times a day?

 

[mitoMAN]

Interesting, a quick google confirmed your statement.
Even though I read exactly the opposite from peptide manufacturers.

But Tailor Made compoundings and even official Zadaxin dosing recommends 2x weekly.

TailorMadecompoundings:
Content & Potency: 1 x 5mL at 3000 mcg/mL ready-to-inject subcutaneous.
Suggested dosage: Inject .15mL subcutaneously once daily until vial is empty (1 month
supply) or inject 1.6mg 2 x 1 week.

Zadaxin:
Chronic Hepatitis B
The recommend-ed dose of ZADAXIN (thymalfasin) for chronic hepatitis B when used as a monotherapy or in combination with interferon (at the labeled dose and schedule for interferon) is 1.6 mg (900 µg/m2) administered subcutaneously twice a week for 6 to 12 months. Patients weighing less than 40 kg should receive a ZADAXIN (thymalfasin) dose of 40 µg/kg.

Another guide:
https://northamptonintegrativemedicine.com/wp-content/uploads/2019/04/Thymosin-alpha-1-Monograph.pdf
Rapidly absorbed, peak serum within 2 hours, 2 hour half-life
Dosage: - SubQ General Dosage - 1.5 mg SubQ every 3rd day - Treatment from 2 weeks for viral infection and 3 months or longer for HIV/cancer /Hepatitis B, C or complicated immune suppression or over-activation - Multiple over-lap of usage Zadaxin™ dosage - 1.6 mg twice weekly for 6-12 months



So I am mainly wondering if HUGE peaks every 3rd day have different effects than daily lower serum levels?

 

[ChookityPop]

So I am mainly wondering if HUGE peaks every 3rd day have different effects than daily lower serum levels?

Im wondering that too. I did 250mcg a day for 1 and a half month or so. I dont know if I noticed anything or not. I didnt get any allergic reactions from birch pollen. That was interesting, though they said it was very little birch pollen where I live also. Im def going to try Ta1 longterm. I think they fused the ta1 in a study with immunoglobulin and made the half life increase to almost 20 hours or something. wonder if it does the same if I take Gammanorm and ta1 at the same time, and the same spot. Probably not? Or mix them.. Maybe thats not safe. or Maybe it is... Ta1 is super interesting and I think the ideal scenario is to use it longterm to see effects.


Edit: its called Thymosin alpha 1-Fc and here is the source https://www.nature.com/articles/s41598-018-30956-y

Among the strategies of extending serum half-life in the body, adding an immunoglobin G (IgG) Fc fragment is one of the most effective technologies. Result shows that the serum half-life of Tα1-Fc was 24.58 h, which is almost 13 times longer than of Tα1

 

[mitoMAN]

I read those study papers too!! Sadly I dont think you can just "combine" the two substances without fusing them somehow in a lab.

I was thinking about contacting those different Peptide podcasts and ask them to do a special show about possible peptide treatments for ME/CFS - which is highly interesting in terms of current COVID!
Maybe someone is interested : )

 

[ChookityPop]

I was thinking about contacting those different Peptide podcasts and ask them to do a special show about possible peptide treatments for ME/CFS - which is highly interesting in terms of current COVID!
Maybe someone is interested : )

Do it! That would be super interesting. Have you tried other peptides? I want to try epitalon.

 

[mitoMAN]

Got Epitalon in the freezer and will try it once I get an idea if TA-1 helps. Maybe in 2-3 weeks.
Also got LL-37 on hand for 12 weeks trial but will wait some more with it.

I also just ordred GHK-cu and might throw that in.

I take rHGH (not the ghrp peptides but the real deal) at 15iu every second day and try to swtich to 8iu daily now with 3 injections per day.

 

[ChookityPop]

Got Epitalon in the freezer and will try it once I get an idea if TA-1 helps. Maybe in 2-3 weeks.
Also got LL-37 on hand for 12 weeks trial but will wait some more with it.

I also just ordred GHK-cu and might throw that in.

I take rHGH (not the ghrp peptides but the real deal) at 15iu every second day and try to swtich to 8iu daily now with 3 injections per day.

Wow! Let us know how you feel. I have to order some too. LL-37 andGHK-cu is very interesting they are on my list too. How does the rHGH make you feel? I want to try that too!

 

[mitoMAN]

for the rHGH, its hard to say, but i THINK it got rid of all my fever like symptoms, shivering attacks, cold skin etc.
Especially my PEM crashes are much much softer.

All in all, I am still in bed for 16+ hours daily but without any pain or similar. Just fatigued.

BUT the real benefit from rHGH should show off after 6-12 months, its something you take for a quite long time and have to keep taking.

My dosage costs about 420€ per month!