I don't find this point convincing as the percentages reporting such adverse events in the APT and SMC-only groups were similar so one can't conclude they were due to CBT or GET.Further, 46% of patients reported increases in their ME/CFS symptoms, 31% reported musculoskeletal, representing the M in ME, and 19% reported neurological adverse events, representing the E in ME [64]. So that the proportion of participants negatively affected by CBT and GET is between 46% and 96%, and most likely estimated at 74%, as recently reported by a large survey conducted by the British ME Association, which involved 1,428 patients [63] and medication with such high rates of adverse events should be withdrawn from the market with immediate effect.
The same point is made in the abstract:
In addition, 46% of patients reported an increase in ME/CFS symptoms, 31% reported musculoskeletal and 19% reported neurological adverse events. Therefore the proportion negatively affected by CBT and GET would be between 46% and 96%, most likely estimated at 74%, as shown in a large survey recently conducted by the ME Association. Medication with such high rates of adverse events would be withdrawn with immediate effect.
And in the conclusion:
The PACE trial found that the proportion negatively affected by CBT and GET was between 46% and 96%, most likely estimated at 74%, as shown in a large survey recently conducted by the ME Association [63]. Medication with such high rates of adverse events would be withdrawn immediately.