Supplementation with high concentrations of synthetic B6 (pyridoxine) leads to decreased natural vitamin B6 (pyridoxal) function

[Don Quixote]

+ Molybdenum


I have run into problems with P5P only, and now I understand this recommendation:

ETA

My supplement has 100mg b6 and 1mg p5p... I still don't really understand why this is, do you know more?

I am hesitant to supplement it though because 100mg of inactive b6 seems like a lot, and having had neurological issues in the past b6 neuropathy worries me.

 

[Pyrrhus]

My supplement has 100mg b6 and 1mg p5p... I still don't really understand why this is

They probably have to provide a minimum of the active form of vitamin B6 (P5P) because some people can not convert the inactive form (pyridoxine) to the active form. Otherwise, these people could develop neuropathy and sue the company for causing their neuropathy.

But they don't like providing it all as P5P, probably because P5P is not as shelf-stable as pyridoxine.

 

[Gondwanaland]

I am hesitant to supplement it though because 100mg of inactive b6 seems like a lot,

Seems like a lot, but I don't know your case.

In my case, it was only after taking pure P5P that my body could process any dose of vit B6...

 

[Gondwanaland]

probably because P5P is not as shelf-stable as pyridoxine

I bought my bottle in 2016 and it looks fine, I still take it and I think it is effective