Might as well share my Valtrex experience here as well.
TL;DR - Feel great! Still very early on though.
Almost 7 weeks into Valacyclovir. Not a lot happened. Then symptoms got much worse all of a sudden. Exactly 6 wks in, had 5 consecutive bedridden days, which is a record for me. Days 4-5 of which included some nausea and headaches, which is not normal for me. But, yesterday, started feeling slightly better. And today, the fatigue lifted completely.
It's only been 2 months and 4 days so far. But, I haven't had any major bedridden experiences, since what I described before. Maybe slightly less PEM. I'd say either same or ever so slightly better since the time of my last post.
At some point, I'll be retesting my EBV levels, hoping to see a decrease in Early Antigen.
I should probably edit my last post (not sure how though). Because I've since found chronic active Echovirus 11, and possible active Chlamydia pneumoniae.
I’m seeing an immunologist that is not that experienced with cfs, but has offered to prescribe me Valacyclovir at 500 mg 2x day, isn’t comfortable going any higher for now. I’m don’t know if that’s going to be enough to have the desired effect. I’m 150 lbs.
Oxymatrine is used for treatment of the echovirus, not sure if you can treat both at the same time. I did entero/echo testing through ARUP lab recently, came back all negative. My EBV has consistently been sky high, no hh6 or cmv. So I think that make me a candidate for the valtrex.
To edit, click the “edit” below your post, make your changes, the hit save.
Just found this, in one of Hip’s posts... In non-responders to Valtrex, Dr Lerner would sometimes add cimetidine (500 mg twice daily) or probenecid (500 mg twice daily), which potentiate blood concentrations of this antiviral drug.
Anyone tried it?
I found these guidelines, going to print and take to my immunologist that gave me the valcyclovir. If I’m going to try this, I’ll have to get her to write scripts and order routine tests, may take some persuading. This plan seems a little more conservative than some of the others. https://www.drpodell.org/ValtrexConsent.pdf
We've discussed this. They have a large anti-inflammatory effect that are most likely causing the improvement and are very expensive. Have you tried a low inflammation diet and time release curcumin which is also anti-inflammatory? Could save you a lot of money and get the same result.
We've discussed this. They have a large anti-inflammatory effect that are most likely causing the improvement and are very expensive. Have you tried a low inflammation diet and time release curcumin which is also anti-inflammatory?
This study shows about 80% sensitivity for cholecystitis inflammation. Tissue areas that are painful (dolor) when you press on them, have signs of swelling (ie. increasing hat size, tigher shoes-tumor), and increased redness (rubor) suggest inflammation. Some viruses (EBV) trigger chronic inflammation by upregulating Nf-kb. I had all of these and they were helped greatly doing this.