Substantial improvement with (strange) dietary adjustments

Dysfunkion

Senior Member
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449
Interesting observation:

*White bread, peanut butter and raw honey --> relatively strong symptoms
*White bread, refrigerated peanut butter, refrigerated raw honey --> no symptoms so far

Probiotic bacteria are known to be abundant in honey:

https://pmc.ncbi.nlm.nih.gov/articles/PMC10336281/

Could the refrigeration slow their activity down until the nutrients they make harmful (to me) compounds from are absorbed or used up by other bacteria?

Could this also work with dates (which I would suspect also contain lots of bacteria)? Could the presence of these bacteria be the reason why porridge with date-berry jam causes symptoms, but not berries alone or porridge alone?

I will explore that further.

I never thought about the temperature of the food. I wonder if refrigerating peanut butter before even heating it would do anything. I kinda doubt it if its changing temperature again when it goes in the oven but its another weird thing to try. I dont know what is going on with gluten based products but I barely touch them anyhow so I'm focusing in this next.
 

Wonkmonk

Senior Member
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1,134
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Germany
I never thought about the temperature of the food.
The symptoms actually appeared yesterday, but much later for the refrigerated honey. I will now try freezing the honey, which should make the bacteria go dormant and take even longer to wake them up. I might also try pasteurizing the honey to test the theory, which should get rid of all the bacteria.
 

Wonkmonk

Senior Member
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Location
Germany
I couldn't make porridge with berries and bread with honey and peanut butter work. It always caused strong symptoms, only the time when they appeared seemed to change with the temperature. Also, cooking the dates for the berry jam didn't help much.

But berries only is ok and dates and berries only also seems ok if meals are splitted into two times 350 calories max each one hour apart. Will try plain peanut butter now. If that works, it would generally support the theory: The bugs need carbs, preferably fructose or fiber, protein and possibly some other compound like choline. Therefore, berries/dates only works (no protein) and peanut butter only should work, too (not much fructose/fiber for the bugs to eat).
 

Wonkmonk

Senior Member
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Location
Germany
Regarding the porridge, the fructose and fiber of the berries and dates cannot be the whole story though because the negative effect is much less pronounced if I eat porridge with bananas with about the same fructose and fiber load.

I suspect that the difference is the berry anthocyanins, which have been shown to affect the composition of the gut microbiota:

https://www.tandfonline.com/doi/full/10.1080/10408398.2023.2187212

https://www.tandfonline.com/doi/full/10.1080/10408398.2018.1533517

My theory is that one or more harmful compounds are produced by one or more otherwise beneficial microbes in the microbiome (or outside the body during fermentation). If so, these microbes seem to thrive when berry anthocyanins are present.

Again, this would offer an avenue to study this disease: Send porridge with bananas and porridge with berries in a artificial stomach (or real subjects) and see what the difference is when it comes out again.
 

Dysfunkion

Senior Member
Messages
449
Regarding the porridge, the fructose and fiber of the berries and dates cannot be the whole story though because the negative effect is much less pronounced if I eat porridge with bananas with about the same fructose and fiber load.

I suspect that the difference is the berry anthocyanins, which have been shown to affect the composition of the gut microbiota:

https://www.tandfonline.com/doi/full/10.1080/10408398.2023.2187212

https://www.tandfonline.com/doi/full/10.1080/10408398.2018.1533517

My theory is that one or more harmful compounds are produced by one or more otherwise beneficial microbes in the microbiome (or outside the body during fermentation). If so, these microbes seem to thrive when berry anthocyanins are present.

Again, this would offer an avenue to study this disease: Send porridge with bananas and porridge with berries in a artificial stomach (or real subjects) and see what the difference is when it comes out again.

Hey this actually makes sense in my case I remember over last Summer as things were getting a lot worse for me one night I remember eating a plum (my crash was due to saw palmetto over the course of a month, was also on lions mane which looking back was probably what primed me for severe) and it was the worst I'd felt yet and not too much further down the line I got tanked to severe for the first time. Many months later on my slow crawl back up I tried anthocyanin in supplement form and instantly regressed quite a bit but thankfully in the next few days I bounced back to my deep moderate baseline at the time. I have also almost gotten into a bad crash that could have tanked me further if I even had the slightest amount more of psyllium husk somewhat recently as taking a tiny sprinkle out of less than half a teaspoon. So I appear to have something that is very reactive to SPECIFIC kinds of fiber and fructose, and in the presence of anthocyanins it goes wild. In fact some fiber may even combat it which is part of my theory on why cinnamon likes my guts so much. I'm also now wondering if cooked salmon produces a compound that directly goes against the offenders and the reason I got better from rebounding off that reaction to it so much is because I was pushing back and another bacterial colony more beneficial was able to gain dominance over it and due to other factors that improved things like cinnamon it was able to keep itself in place. I also noticed the more coffee I consume but not caffeine alone which barely does anything for me itself the better off I am, propolis is also crucial for me. The trend seems to be that high plant polyphenols plus rebounding off of salmon is what pushes me back to mild island.

I'm highly reactive to fruit, even recently I found tomato isn't much better than any traditional sweet fruits like apple or mango. Anything apple is the second to worse followed by plums which was one of the worst reactions to anything I had ever (I haven't tried any of the others high in anthocyanins). I have a funny feeling our microbiomes are pretty similar if this is the case but I have a lot more of something that tanks me much faster with fructose. It's not a sugar thing, I can eat all the white and brown sugar in the world and just feel a bit slower (I almost never do, maybe once in a blue moon I might have some ice cream or some cookies). Carbs and sugars may feed it but the show only really begins when fructose and now likely anthocynanins join the party. Keeping the glutamate level very low also seems to be part of keeping things running smoothly, soy sauce or tofu both make things much worse but in different ways. I don't think histamine is really part of my big picture even if it can get higher than it should sometimes, it may actually even be something my body isn't responding enough to, I remember when I was in severe and deep moderate if I had something with a ton of histamine I would feel nothing whereas before histamine would actually make me feel more wired and stimulated in a very raw way. Cortisol would also do just about nothing, one time I ate a whole capsule of adrenal cortex and just felt like I was going to have a muted panic attack.

What do you mean by outside of the body though, the skin microbiome or what is produced traveling through the body to the surface of the skin?
 

Wishful

Senior Member
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6,194
Location
Alberta
Will try plain peanut butter now.
Keep in mind that not all "plain PBs" are identical. I do seem intolerant of one brand, while tolerant of another. Different effectiveness of embryo removal? Different soils or climate? Different storage times and conditions? Different microbes on/in them?

Biology is not as simple as inorganic chemistry, where all NaCl molecules are identical ... unless isotopic ratios make a difference.
 
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