The starting dose for hypothyroidism is typically around 100 mcg of T4.I'm not a doctor, but I don't think you would notice a difference that quickly, maybe more like 2-3 weeks. Let's just hope it was a glimmer of good things to come. Anyway, I am very curious how a starting dose off 88 mcg was determined. I thought the general protocol was to start off with 25 mcg.
My mother takes synthroid and she has blood tests to determine what the dose should be.
Synthroid is T4 which your body turns into T3. Cortisol is needed to get T3 into your cells. Extra T3 will mean that your body needs extra cortisol. If your adrenals are not up to the task, this can cause problems. Your body can also turn T4 into reverse T3, which is useless so won't cause adrenal problems.
I used to take Synthroid and i'm pretty sure it made my illness worse. After about a year of being on it during a remission phase i was gradually getting sicker, and sicker, until I flared back up into a full blown episode. My new doctor got me off it immediately and the icky feelings(nausea, weird heart beat, and other such uncomfortable symptoms) died down over time. I have ridiculously high cortisol levels that the old doctor hadn't tested for..so that probably didn't help a dang thing.
Also, gained weighed on the stuff instead of loosing, which didn't make me like it even more, haha.