Running out of treatment options. What next?

dreamydays

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See my experience on Tofacitinib hereN
https://forums.phoenixrising.me/threads/tofacitinib-2-month-trial.80915/

People talked about JAK inhibitors before but I didn't get much interest in my trial. I do trials do help me obviously, but I genuinely think I am also taking a risk taking new unsupervised trials to help all of us out of this hell. I also posted a few other trials and a way I get of going from bedbound to housebound and physically doing things and didn't get much response. Well its good to see people talking about medication rather than taking garlic or whatever

Upadacitinib blocks more JAK pathways, but i don't think it will be easy to get and at the time i looked into JAK enzymes and i'm not sure if blocking. more will chsnge anything. But I would try it at the right price because I am a guinea pig!

Not sure if its been mentioned but I stopped NMN 1g for NAD+ subcutaneous injections and the NAD+ is so much better, You have to prepare it properly though but i'm sure there is a guide some where. nadlab uk sell alive by nature sublingual nad+ which you can use under your tongue but you struggle to absorb enough that way but there is no additives so you could use that so subq injections. @mitoMAN put me on to this but he gets more out of NADH. NAD+ in theory would work better in terms of its actions but NADH will get recycled into NAD+ eventually. My injections cost the same as the NMN or less if you respond to a lower lose
 

dreamydays

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Curcumin has no effect on me, plus you need piperine to absorb more and that just fucks up your hormones and half the drugs in the world. only herbal type that work as far as i've tried are holy basil 5g organic powder in water with sweeteners to cover the bitter taste (you could also use d-ribose if it works for you) and Oxymatrine which their are threads on. To be fair neem is good as an oral antifungal which can be useful.
 

mitoMAN

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Curcumin has no effect on me, plus you need piperine to absorb more and that just fucks up your hormones and half the drugs in the world. only herbal type that work as far as i've tried are holy basil 5g organic powder in water with sweeteners to cover the bitter taste (you could also use d-ribose if it works for you) and Oxymatrine which their are threads on. To be fair neem is good as an oral antifungal which can be useful.
I ordered liquid nano curcumin for injection purpose along with water solube Q10. Will keep you posted mate.

Also @dreamydays you could try injectible NMN and NR. I have both sitting in my freezer - I noticed improvment on NMN for a few days then had a crash. So I only tried NMN injections from 300-600mg per 5 days.