Now it is just an B cell level that is measured maybe @Jonathan Edwards could shed some light on it as I am a bit confused about the levels and their meanings as well.
Now it is just an B cell level that is measured maybe @Jonathan Edwards could shed some light on it as I am a bit confused about the levels and their meanings as well.
B cell levels vary widely in normal blood. They probably do not mean much because B cells only pass through blood very transiently. They do not do anything there. It is a bit like trying to gauge how many people live in a town by looking out of the window to see how many people are on the street. As far as I know counts tell us nothing about autoimmune disease. (They are very high in B cell leukaemia but that is a completely different issue.) I have not seen any evidence that high or low counts affect response to rituximab in any autoimmune disease.
On a wider front counts of lymphocyte populations in individual people are not very likely to tell us much in ME/CFS. There may be statistical trends across groups of ME patients of interest but one off measurements for single individuals probably mean nothing.