I can't say I'm surprised given that many people on a ketogenic diet are eating a lot of red meat, cream, butter etc. I personally can't tolerate carbohydrates/sugar and my diet is mostly lots low-carb vegetables, seafood, chicken, eggs, and some dairy.
That's why I mentioned it. Unhealthy fats seem to be the main driver for almost all the risks they identified. There's still an argument to be made if a high protein diet can affect the kidneys negatively but it might as well be the cardiovascular vector that affects the kidneys via high blood pressure.
Red meat is one of the greatest concerns for colon cancer. A "cheating" keto diet that doesn't integrate a lot of healthy fats will not improve health. Pushing the ketogenesis margin won't be helpful for insulin sensitivity either. But it's possible that the diabetes risk is somehow confounded by selection or not filtered for sufficient ketogenesis persistence.
I'm still convinced that the keto diet is a very healthy diet if it's done properly with healthy fats, especially olive oil. It's part of the human evolution and leaving fasting or the ketogenesis out of the normal life cycle prevents important metabolic steps to take place.
During summer, humans are supposed to gain weight, build muscle, push growth hormones. In the winter up to spring, this is supposed to inverse, fasting period is supposed to take place, the gained weight is supposed to be lost, apoptosis is supposed to happen, senescent cells are supposed to be cleared out.
That's about the time frame the human organism is supposed to follow. Ketogenesis isn't supposed to happen endlessly. However, it's unclear how long you initially need to basically catch up with all the missed fasting periods. And technically, ketosis is supposed to be starvation, but intermittent fasting might work almost as well, and not everyone has weight to lose, so I try not to fast at all but gain weight that I couldn't gain in gluconeogenesis.
Unfortunately, long-term improvement in ketogenesis appears to remain elusive...
I still feel better than before, but I'm also part of the ME subgroup that generally noticed worsening from sugars, just like @Shanti1
. I noticed repetitive improvements of ME symptoms combined with a worsening of pain. I'm not sure if it's a natural reaction because of my high susceptibility to reactive rheumatic autoimmunity or if it's fibromyalgia or reactivation of borreliosis or a zoster virus. It's always either ME or pain, no complete remission. I have never had such a back pain ever before the keto diet.
Once, I have already tried to leave ketosis but it only lead to hyperglycemia, which can become an urgent emergency while being in ketosis. I'll only dare to repeat this in the presence of a physician with an insulin shot at the ready.
I agree. I guess it's just like with vitamins. Sometimes, you find meta-reviews that point out all the negatives like there aren't any positives. Ketosis is a natural part of our organism and useful for more people than just epileptics. I think it's a powerful tool for overweight people who want to become healthy and lose weight while still being able to work and think clearly, which isn't possible with these typical low calorie diets. It's also ideal to keep your weight because there's no strong reward mechanism for eating fats without sugars. My personal experience is that it's quite difficult to reach so much fat intake that a gain in weight is even possible. So many people nowadays just overeat everything. The GIS doesn't like that, even if it's vegan only.