Relevance of studies of cellular receptors to the prevention and control of viral disease:

[Violeta]

https://apps.who.int/iris/bitstream/handle/10665/265191/PMC2536479.pdf?sequence=1&isAllowed=y

Viruses exhibit specificities in their abilities to replicate at the species, tissue and cellular level.

A number of viruses appear to recognize proteins of known physiological function, e.g., rabies virus possibly recognizes the acetylcholine receptor; Epstein-Barr virus, the C3 complement receptor; and reoviruses, the beta adrenergic receptor.

 

[wastwater]

Lowered complement C3 in the liver is interesting

And an article about covid and liver

How could an existing liver disease drug help reduce COVID cases?


https://www.weforum.org/agenda/2022/12/existing-liver-disease-drug-help-reduce-covid-cases/

 

[Violeta]

Epstein-Barr virus, the C3 complement receptor;

What does C3 complement do?


This is an important part of your immune system. It helps kill bacteria and viruses that cause disease. C3 protein is the most important and abundant protein in the complement system. It covers microbes to destroy them.

So Epstein-Barr virus enters at the C3 complement receptor, but the C3 complement receptor helps kill bacteria and viruses that cause disease.

 

[wastwater]

I wondered if covid may also decrease C3 and maybe this is why we are seeing more bacterial infections in children as it has a worse impact in the younger years

https://www.ncbi.nlm.nih.gov/gtr/conditions/C1332655/