ljimbo423
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Though I find it hard to see how the forces of evolution would create a human body so shoddy that it falls into these self-sustaining metabolic traps. Our genetic makeup has evolved over billions of years, and Prof Paul Ewald argues that any gene which gives rise to disease would have been eliminated by now (with certain exceptions). So from this Ewald perspective, it's hard to explain how a self-sustaining metabolic trap would arise genetically. This is why Ewald argues that diseases are most likely caused by exogenous agents in the form of pathogens.
I agree completely. It doesn't make sense to me that the CDR would somehow become locked or stuck. I think he's got this wrong and there has to be something keeping the CDR in place.
I also think that a pathogenic cause will be found. It just seems to fit to me.