Degree in physics, with a long interest in health, supplements and smart drugs (nootropics); but no medical education as such.
In fact I did not realize how little I knew about biology until I got hit with ME/CFS in 2006, and started reading a bit about medical science, virology and immunology in order to try to improve my health. In some ways, it was nice to be given the opportunity to read more about biology, as being housebound I have a lot of time. That's about the only plus side I can think of in this otherwise miserable experience with ME/CFS.
I still know very, very little in general about medicine, but have picked up a few bits of knowledge about ME/CFS-related science.
The trouble is, the enterovirus infections found in ME/CFS are not regular infections. You do not actually have many viral particles being created.
Rather the infection exists as a self-replicating strand of viral dsRNA that lives long-term inside
human cells. This viral dsRNA is completely naked within the cell; it is not contained within a viral particle shell.
This intracellular form of viral dsRNA infection is known as non-cytolytic enterovirus
, and it's quite a complex beast to understand. There is an MEpedia article here
. And a thread here
Chronic non-cytolytic enterovirus infection is also found in other diseases: in type 1 diabetes, and in heart diseases like chronic myocarditis.
The body's natural interferon response would normally clear cells of this enteroviral dsRNA, but there is a theory by Lévêque (briefly explained in the article) that the dsRNA becomes resistant to interferon.
So to answer your question: the dsRNA infection in patients with enterovirus ME/CFS is located within human cells as a chronic intracellular infection. Therefore being inside the cell, it has some protection from whatever you are going to throw at it.
I spent countless hours trying to figure out some way of tackling this dsRNA (as indeed has Dr John Chia), but so far I have not come up with much.