A paraneoplastic panel screens for autoantibodies to that cause neurological issues and many other issues with the body. This panel is associated with small cell cancer in several areas of the body but can also exist without cancer. It can present exactly like ME in some cases with similar symptom overlap.
http://www.mayomedicallaboratories.com/test-catalog/Overview/83380
The panel is done by the Mayo Clinic but also in Canada, US, UK, etc.
A ME soecialist will do a thorough workup of all know viruses, bacterias, parasites that may be reactivated. As well as the state of your immhne system and other testing as well. They will also provide treatment protocols based on findings.
In Canada there are probably 2 experts.
UK has one Dr Myhill.
US Dr. Chia, Petterson, Montoya, Klimas, Kaufman, etc.
Belgium/US Dr Kenny De Meirleir
There is also one in Germany I forget his name.