- Messages
- 171
- Location
- London
Hey,
I keep trying to figure out as to whether or not progesterone is a bad thing in this disease. I'm aware that it's been found to increase XMRV replication. However I know that a deficiency of it can lead to many issues aswell. So I decided to try it. I took 1 tablet of micronized progesterone - I believe it is a synthetic version, maybe not the best form - but I tried the cream and I could feel no effect.
So some time after taking the progesterone I noticed a rather pronounced improvement in my energy and fatigue (or lack of therefore). This improvement lasted for several hours up until a point where I started to get an ever worsening migraine. The sockets of my eyeballs felt as if someone was pressing on them. And a sensation which can only be described as a feeling of severe pressure in the brain. It was almost as if my brain was inflamed or perhaps this sensation was due to water accumulation putting pressure on the tissues?
I find this reaction puzzling because on the one hand it markedly helped symptoms a lot, (progesterone has many anti-inflammatory properties and a metabolite acts as a GABA A receptor agonist...?!), but then later i felt in significant discomfort (could this in any way be increasing XMRV replication this quickly - i wouldn't have thought so?)
Please share your experiences with progesterone and any insight into these good and bad reactions! It's frustrating because initally it made a pronounced improvement to my symptoms!
Jake
I keep trying to figure out as to whether or not progesterone is a bad thing in this disease. I'm aware that it's been found to increase XMRV replication. However I know that a deficiency of it can lead to many issues aswell. So I decided to try it. I took 1 tablet of micronized progesterone - I believe it is a synthetic version, maybe not the best form - but I tried the cream and I could feel no effect.
So some time after taking the progesterone I noticed a rather pronounced improvement in my energy and fatigue (or lack of therefore). This improvement lasted for several hours up until a point where I started to get an ever worsening migraine. The sockets of my eyeballs felt as if someone was pressing on them. And a sensation which can only be described as a feeling of severe pressure in the brain. It was almost as if my brain was inflamed or perhaps this sensation was due to water accumulation putting pressure on the tissues?
I find this reaction puzzling because on the one hand it markedly helped symptoms a lot, (progesterone has many anti-inflammatory properties and a metabolite acts as a GABA A receptor agonist...?!), but then later i felt in significant discomfort (could this in any way be increasing XMRV replication this quickly - i wouldn't have thought so?)
Please share your experiences with progesterone and any insight into these good and bad reactions! It's frustrating because initally it made a pronounced improvement to my symptoms!
Jake